Evidence map›Paper›PMID 27881723›Full record

ArticleJournal of neurophysiology2017

Intraspinal microstimulation and diaphragm activation after cervical spinal cord injury.

L M Mercier, E J Gonzalez-Rothi, K A Streeter, S S Posgai, A S Poirier, D D Fuller, P J Reier, D M Baekey

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Frontiers in bioengineering and biotechnology · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Regulation of Human Respiration by Electrical Stimulation.Journal of evolutionary biochemistry and physiology · 2022
    Article
  12. Article
  13. Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Review
  14. Article
  15. Review
  16. Review
  17. Respiratory resetting elicited by single pulse spinal stimulation.Respiratory physiology & neurobiology · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

L M MercierDepartment of Neuroscience, University of Florida, Gainesville, Florida.
E J Gonzalez-RothiDepartment of Physical Therapy, University of Florida, Gainesville, Florida; and.
K A StreeterDepartment of Physical Therapy, University of Florida, Gainesville, Florida; and.
S S PosgaiDepartment of Neuroscience, University of Florida, Gainesville, Florida.
A S PoirierDepartment of Physical Therapy, University of Florida, Gainesville, Florida; and.
D D FullerDepartment of Physical Therapy, University of Florida, Gainesville, Florida; and.
P J ReierDepartment of Neuroscience, University of Florida, Gainesville, Florida.
D M BaekeyDepartment of Physiological Sciences, University of Florida, Gainesville, Florida dbaekey@ufl.edu.
University of Florida · US

Funding

Training In Rehabilitation and Neuromuscular PlasticityT32HD043730 · NICHD · UNIVERSITY OF FLORIDA · PI DAVID D FULLER · 2003 to 2026
$5.3M
Plasticity and Repair in the Phrenic Motor SystemR01NS054025 · NINDS · UNIVERSITY OF FLORIDA · PI REIER, PAUL J · 2006 to 2015
$3.0M
NICHD NIH HHS T32 HD043730NINDS NIH HHS R01 NS054025
6 · The paper itself

Abstract

Intraspinal microstimulation (ISMS) using implanted electrodes can evoke locomotor movements after spinal cord injury (SCI) but has not been explored in the context of respiratory motor output. An advantage over epidural and direct muscle stimulation is the potential of ISMS to selectively stimulate components of the spinal respiratory network. The present study tested the hypothesis that medullary respiratory activity could be used to trigger midcervical ISMS and diaphragm motor unit activation in rats with cervical SCI. Studies were conducted after acute (hours) and subacute (5-21 days) C

Indexed as

Analysis of VarianceAnimalsBiomechanical PhenomenaBiophysicsCervical CordDiaphragmDisease Models, AnimalElectric StimulationElectromyographyFemaleRatsRats, Sprague-DawleyRecovery of FunctionSpinal CordSpinal Cord Injuriesdiaphragm functionhypoglossal respiratory activityphrenic motor nucleusratrespiration

Identifiers

PMID27881723
PMCPMC5304410
OpenAlexW2553474139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.