ReviewJournal of the American Society of Nephrology : JASN2017
Bicarbonate Balance and Prescription in ESRD.
Review in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 51 citations in OpenAlex.
- Effect of time-dependent dialysate bicarbonate concentrations on acid-base and uremic solute kinetics during hemodialysis treatments.Scientific reports · 2024Trial
- Mathematical modeling of peritoneal buffer transport and acidosis correction in patients on peritoneal dialysis.Scientific reports · 2026Article
- The Association of Serum Bicarbonate With Psychological and Physical Health-Related Quality of Life in Patients Receiving Maintenance Hemodialysis: A Secondary Analysis of the Frequent Hemodialysis Network Daily Trial.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2026Article
- Effect of dialysate bicarbonate on calciprotein particle crystallization time (T50) in hemodialysis patients-the D-Bic study.Clinical kidney journal · 2025Article
- Concurrent Control of Sodium and Bicarbonate Serum Concentrations Using a Four-Stream Hemodialysis Fluid Delivery System.Hemodialysis international. International Symposium on Home Hemodialysis · 2025Article
- Association of Dialysate Bicarbonate with Arrhythmia in the Monitoring in Dialysis Study.Kidney360 · 2024Article
- Hemodialysis Procedures for Stable Incident and Prevalent Patients Optimize Hemodynamic Stability, Dialysis Dose, Electrolytes, and Fluid Balance.Journal of clinical medicine · 2024Review
- Association Between the Dialysate Bicarbonate and the Pre-dialysis Serum Bicarbonate Concentration in Maintenance Hemodialysis: A Retrospective Cohort Study.Canadian journal of kidney health and disease · 2024Article
- Point-of-Care Chemistry-Guided Dialysate Adjustment to Reduce Arrhythmias: A Pilot Trial.Kidney international reports · 2023Article
- Mathematical modelling of bicarbonate supplementation and acid-base chemistry in kidney failure patients on hemodialysis.PloS one · 2023Article
- Acid-base balance in hemodialysis patients in everyday practice.Renal failure · 2022Article
- Review
- Tailoring the dialysate bicarbonate eliminates pre-dialysis acidosis and post-dialysis alkalosis.Clinical kidney journal · 2022Article
- Treatment of Metabolic Acidosis in Hemodialysis Patients Is Biased by Type of Vascular Access.Kidney international reports · 2022Article
- Dialysis Disequilibrium: Is Acidosis More Important than Urea?Case reports in nephrology · 2022Article
- Water-powered self-propelled magnetic nanobot for rapid and highly efficient capture of circulating tumor cells.Communications chemistry · 2021Article
- Precision medicine in transplantation and hemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Article
- Relationship between mortality and use of sodium bicarbonate at the time of dialysis initiation: a prospective observational study.BMC nephrology · 2021Observational
- Optimization of dialysate bicarbonate in patients treated with online haemodiafiltration.Clinical kidney journal · 2021Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The optimal approach to managing acid-base balance is less well defined for patients receiving hemodialysis than for those receiving peritoneal dialysis. Interventional studies in hemodialysis have been limited and inconsistent in their findings, whereas more compelling data are available from interventional studies in peritoneal dialysis. Both high and low serum bicarbonate levels associate with an increased risk of mortality in patients receiving hemodialysis, but high values are a marker for poor nutrition and comorbidity and are often highly variable from month to month. Measurement of pH would likely provide useful additional data. Concern has arisen regarding high-bicarbonate dialysate and dialysis-induced alkalemia, but whether these truly cause harm remains to be determined. The available evidence is insufficient for determining the optimal target for therapy at this time.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.