ArticleGenes & development2016
Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
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Article in Genes & development, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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50citing papers in PubMed
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Who cites it
50 citing papers in PubMed, 76 citations in OpenAlex.
- N7-Methylguanosine Modification in Colorectal Cancer: Molecular Insights and Clinical Implications.International journal of molecular sciences · 2026Review
- Domain-selective folding of the tandem β-propeller protein Coronin 7 (Coro7) by the chaperonin CCT/TRiC.The Journal of biological chemistry · 2026Article
- Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding.RNA biology · 2025Article
- Proteins that recognize unique features of U7 snRNA and may substitute for Gemin5 in the assembly of U7-specific Sm ring.RNA (New York, N.Y.) · 2025Article
- Application of Biomarkers in Spinal Muscular Atrophy.International journal of molecular sciences · 2025Review
- Developmental and Epileptic Encephalopathy: Pathogenesis of Intellectual Disability Beyond Channelopathies.Biomolecules · 2025Review
- Article
- Oligomerization regulates the interaction of Gemin5 with members of the SMN complex and the translation machinery.Cell death discovery · 2024Article
- 1-L Transcription of SARS-CoV-2 Spike Protein S1 Subunit.International journal of molecular sciences · 2024Article
- Alternative splicing events driven by altered levels of GEMIN5 undergo translation.RNA biology · 2024Article
- The SMN complex drives structural changes in human snRNAs to enable snRNP assembly.Nature communications · 2023Article
- Mechanism of assembly of snRNP cores assisted by ICln and the SMN complex in fission yeast.iScience · 2023Article
- SMN regulates GEMIN5 expression and acts as a modifier of GEMIN5-mediated neurodegeneration.Acta neuropathologica · 2023Article
- MDiscover oncology · 2023Article
- Bi-allelic SNAPC4 variants dysregulate global alternative splicing and lead to neuroregression and progressive spastic paraparesis.American journal of human genetics · 2023Article
- Expression pattern, tumor immune landscape, and prognostic value of N7‑methylguanosine regulators in bladder urothelial carcinoma.Oncology letters · 2023Article
- Structural basis for Gemin5 decamer-mediated mRNA binding.Nature communications · 2022Article
- Gemin5-dependent RNA association with polysomes enables selective translation of ribosomal and histone mRNAs.Cellular and molecular life sciences : CMLS · 2022Article
- Functional and structural deficiencies of Gemin5 variants associated with neurological disorders.Life science alliance · 2022Article
- m7G regulator-mediated molecular subtypes and tumor microenvironment in kidney renal clear cell carcinoma.Frontiers in pharmacology · 2022Article
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Authors and funding
13 authors at 6 institutions in 4 countries.
Chao XuHefei National Laboratory for Physical Sciences at Microscale, Hefei Science Center of CAS, Chinese Academy of Science, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
Hideaki IshikawaDepartment of Applied Biological Science, Graduate School of Agriculture and Global Innovation Research Organization, Tokyo University of Agriculture and Technology, Fuchu-Shi, Tokyo 183-8509, Japan.
Keiichi IzumikawaDepartment of Applied Biological Science, Graduate School of Agriculture and Global Innovation Research Organization, Tokyo University of Agriculture and Technology, Fuchu-Shi, Tokyo 183-8509, Japan.
Li LiStructural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Hao HeStructural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Yuko NobeDepartment of Chemistry, Tokyo Metropolitan University, Hachiouji-shi, Tokyo 192-0397, Japan.
Yoshio YamauchiDepartment of Chemistry, Tokyo Metropolitan University, Hachiouji-shi, Tokyo 192-0397, Japan.
Hanief M ShahjeeDepartment of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Xian-Hui WuStructural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Yi-Tao YuDepartment of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Toshiaki IsobeDepartment of Chemistry, Tokyo Metropolitan University, Hachiouji-shi, Tokyo 192-0397, Japan.
Nobuhiro TakahashiDepartment of Applied Biological Science, Graduate School of Agriculture and Global Innovation Research Organization, Tokyo University of Agriculture and Technology, Fuchu-Shi, Tokyo 183-8509, Japan.
Jinrong MinStructural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Tokyo Metropolitan University · JPTokyo University of Agriculture and Technology · JPStructural Genomics Consortium · CAUniversity of Rochester · USUniversity of Toronto · CAUniversity of Science and Technology of China · CN
Funding
Expanding the genetic code by targeted pseudouridylationR01GM104077 · NIGMS · UNIVERSITY OF ROCHESTER · PI YU, YI-TAO · 2012 to 2015
$1.2MRegulation of telomerase activity and aging by 2'-O-methylation in telomerase RNAR21AG039559 · NIA · UNIVERSITY OF ROCHESTER · PI YU, YI-TAO · 2012 to 2013
$412kNIA NIH HHS R21 AG039559NIGMS NIH HHS R01 GM104077Wellcome Trust
Abstract
In cytoplasm, the survival of motor neuron (SMN) complex delivers pre-small nuclear RNAs (pre-snRNAs) to the heptameric Sm ring for the assembly of the ring complex on pre-snRNAs at the conserved Sm site [A(U)
Indexed as
Models, MolecularBinding SitesCell LineCrystallizationHEK293 CellsHumansPoint MutationProtein BindingProtein DomainsProtein Structure, TertiaryProtein TransportRibonucleoproteins, Small NuclearRNA PrecursorsSMN Complex ProteinsRibonucleoproteins, Small NuclearRNA PrecursorsSMN Complex ProteinsSMN complexWD40 domainX-ray crystal structure
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.