Evidence map›Paper›PMID 27881419›Full record

ArticleApplied and environmental microbiology2017

Oral Administration of a Select Mixture of Bacillus Probiotics Affects the Gut Microbiota and Goblet Cell Function following Escherichia coli Challenge in Newly Weaned Pigs of Genotype MUC4 That Are Supposed To Be Enterotoxigenic E. coli F4ab/ac Receptor Negative.

Wei Zhang, Yao-Hong Zhu, Dong Zhou, Qiong Wu, Dan Song, Johan Dicksved, Jiu-Feng Wang

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 110 citations in OpenAlex.

  1. Nutrients · 2019
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. MaternalComputational and structural biotechnology journal · 2025
    Article
  8. Article
  9. Article
  10. Dietary Triple-StrainMicroorganisms · 2024
    Article
  11. Article
  12. Frontiers in veterinary science · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Effects of EnterotoxigenicMicroorganisms · 2023
    Article
  17. Review
  18. Article
  19. Effects of DietaryAnimals : an open access journal from MDPI · 2023
    Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Wei ZhangDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yao-Hong ZhuDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China zhu_yaohong@hotmail.com.
Dong ZhouDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Qiong WuDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Dan SongDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Johan DicksvedDepartment of Animal Nutrition and Management, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Jiu-Feng WangDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China.
China Agricultural University · CNSwedish University of Agricultural Sciences · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structural disruption of the gut microbiota and impaired goblet cell function are collateral etiologic factors in enteric diseases. Low, moderate, or high doses of a Bacillus licheniformis-B. subtilis mixture (BLS mix) were orally administered to piglets of genotype MUC4 that are supposed to be F4-expressing enterotoxigenic Escherichia coli strain (F4 IMPORTANCE: The present study is important for improving our understanding of the protective role of probiotics against Escherichia coli infection in piglets. Structural disruption of the gut microbiota and impaired goblet cell function are collateral etiologic factors in enteric diseases. In this study, low, moderate, or high doses of a Bacillus licheniformis-B. subtilis mixture (BLS mix) were orally administered to MUC4-resistant piglets for 1 week before the F4-expressing ETEC strain (F4

Indexed as

Administration, OralAnimal FeedAnimalsBacillus licheniformisBacillus subtilisDietEnterotoxigenic Escherichia coliEscherichia coli InfectionsFemaleGastrointestinal MicrobiomeGenotypeGoblet CellsMaleMucin-4ProbioticsSus scrofaMucin-4Bacillus licheniformisBacillus subtilisEscherichia coligoblet cellgut microbiotapig

Identifiers

PMID27881419
PMCPMC5244294
OpenAlexW2555145964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.