Evidence map›Paper›PMID 27880908›Full record

ArticleCell reports2016

Conditional Loss of Pten in Myogenic Progenitors Leads to Postnatal Skeletal Muscle Hypertrophy but Age-Dependent Exhaustion of Satellite Cells.

Feng Yue, Pengpeng Bi, Chao Wang, Jie Li, Xiaoqi Liu, Shihuan Kuang

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 84 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Cells · 2025
    Article
  7. Overexpression of CPT1A disrupts the maintenance and regenerative function of muscle stem cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  8. Article
  9. Article
  10. Emerging role of vitamin DAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Feng YueDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Pengpeng BiDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Chao WangDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Jie LiDepartment of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.
Xiaoqi LiuDepartment of Biochemistry, Purdue University, West Lafayette, IN 47907, USA; Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.
Shihuan KuangDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA; Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA. Electronic address: skuang@purdue.edu.
Purdue University West Lafayette · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI Andrea L Kasinski · 1985 to 2026
$43.4M
Treatment of Castration-resistant Prostate Cancer (CRPC)R01CA196835 · NCI · UNIVERSITY OF KENTUCKY · PI LIU, XIAOQI · 2016 to 2020
$1.7M
PTEN Function in Satellite CellsR01AR071649 · NIAMS · PURDUE UNIVERSITY · PI KUANG, SHIHUAN · 2017 to 2021
$1.7M
Notch Regulation of Stem Cell Fate in MuscleR01AR060652 · NIAMS · PURDUE UNIVERSITY · PI KUANG, SHIHUAN · 2010 to 2014
$1.6M
NCI NIH HHS P30 CA023168NCI NIH HHS R01 CA196835NIAMS NIH HHS R01 AR060652NIAMS NIH HHS R01 AR071649
6 · The paper itself

Abstract

Skeletal muscle stem cells (satellite cells [SCs]) are normally maintained in a quiescent (G

Indexed as

Muscle DevelopmentAgingAnimalsAnimals, NewbornCell DifferentiationCell ProliferationCells, CulturedDenervationGene DeletionHypertrophyMice, KnockoutMuscle, SkeletalMuscular AtrophyMyoD ProteinPTEN PhosphohydrolaseRegenerationMyoD ProteinPTEN PhosphohydrolaseaginghypertrophyPtenregenerationskeletal musclestem cells

Identifiers

PMID27880908
PMCPMC5181649
OpenAlexW2556789641

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.