ArticleCortex; a journal devoted to the study of the nervous system and behavior2017
Hippocampal and diencephalic pathology in developmental amnesia.
Article in Cortex; a journal devoted to the study of the nervous system and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Reevaluating the role of the hippocampus in memory: A meta-analysis of neurotoxic lesion studies in nonhuman primates.Hippocampus · 2023Pooled it
- Diencephalic integrity explains aspects of hippocampal amnesia.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Article
- Review
- Cognitive outcome and its neural correlates after cardiorespiratory arrest in childhood.Developmental science · 2024Article
- Review
- The amygdala is not necessary for the familiarity aspect of recognition memory.Nature communications · 2023Article
- Structural plasticity in the entorhinal and perirhinal cortices following hippocampal lesions in rhesus monkeys.Hippocampus · 2023Article
- Korsakoff's Syndrome and Alzheimer's Disease-Commonalities and Specificities of Volumetric Brain Alterations within Papez Circuit.Journal of clinical medicine · 2023Article
- Brain volumes and functional outcomes in children without cerebral palsy after therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy.Developmental medicine and child neurology · 2023Article
- Intact high-resolution working memory binding in a patient with developmental amnesia and selective hippocampal damage.Hippocampus · 2022Article
- A Rare Case of Complete Absence of Mammillary Bodies on Imaging.Journal of neurosciences in rural practice · 2022Article
- The Mammillary Bodies: A Review of Causes of Injury in Infants and Children.AJNR. American journal of neuroradiology · 2022Review
- When the brain, but not the person, remembers: Cortical reinstatement is modulated by retrieval goal in developmental amnesia.Neuropsychologia · 2021Article
- Sexual Dimorphisms and Asymmetries of the Thalamo-Cortical Pathways and Subcortical Grey Matter of Term Born Healthy Neonates: An Investigation with Diffusion Tensor MRI.Diagnostics (Basel, Switzerland) · 2021Article
- Mammillary body atrophy and other MRI correlates of school-age outcome following neonatal hypoxic-ischemic encephalopathy.Scientific reports · 2021Observational
- Preserved visual memory and relational cognition performance in monkeys with selective hippocampal lesions.Science advances · 2020Article
- Volume reduction of caudate nucleus is associated with movement coordination deficits in patients with hippocampal atrophy due to perinatal hypoxia-ischaemia.NeuroImage. Clinical · 2020Article
- Signal Change in the Mammillary Bodies after Perinatal Asphyxia.AJNR. American journal of neuroradiology · 2019Article
- Mammillothalamic Disconnection Alters Hippocampocortical Oscillatory Activity and Microstructure: Implications for Diencephalic Amnesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Developmental amnesia (DA) is a selective episodic memory disorder associated with hypoxia-induced bilateral hippocampal atrophy of early onset. Despite the systemic impact of hypoxia-ischaemia, the resulting brain damage was previously reported to be largely limited to the hippocampus. However, the thalamus and the mammillary bodies are parts of the hippocampal-diencephalic network and are therefore also at risk of injury following hypoxic-ischaemic events. Here, we report a neuroimaging investigation of diencephalic damage in a group of 18 patients with DA (age range 11-35 years), and an equal number of controls. Importantly, we uncovered a marked degree of atrophy in the mammillary bodies in two thirds of our patients. In addition, as a group, patients had mildly reduced thalamic volumes. The size of the anterior-mid thalamic (AMT) segment was correlated with patients' visual memory performance. Thus, in addition to the hippocampus, the diencephalic structures also appear to play a role in the patients' memory deficit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.