ArticlePloS one2016
Feasibility of Quantification of Intracranial Aneurysm Pulsation with 4D CTA with Manual and Computer-Aided Post-Processing.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Analysis of Intracranial Aneurysm Haemodynamics Altered by Wall Movement.Bioengineering (Basel, Switzerland) · 2024Article
- Quantification of morpho-hemodynamic changes in unruptured intracranial aneurysms with irregular pulsation during the cardiac cycle using 4D-CTA.Frontiers in neurology · 2024Article
- Dynamic evaluation of unruptured intracranial aneurysms by 4D-CT angiography: comparison with digital subtraction angiography (DSA) and surgical findings.BMC medical imaging · 2023Article
- Dynamic Computed Tomography Angiography for capturing vessel wall motion: A phantom study for optimal image reconstruction.PloS one · 2023Article
- A review on imaging techniques and quantitative measurements for dynamic imaging of cerebral aneurysm pulsations.Scientific reports · 2021Review
- Analysis of the influence of imaging-related uncertainties on cerebral aneurysm deformation quantification using a no-deformation physical flow phantom.Scientific reports · 2018Article
- Quantification of Intracranial Aneurysm Volume Pulsation with 7T MRI.AJNR. American journal of neuroradiology · 2018Article
- Diagnostic Work-Up of a Giant Calcified Intracranial Aneurysm: Comparing 4D-CTA and Cerebral Angiogram Findings.Cureus · 2017Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe analysis of the pulsation of unruptured intracranial aneurysms might improve the assessment of their stability and risk of rupture. Pulsations can easily be concealed due to the small movements of the aneurysm wall, making post-processing highly demanding. We hypothesized that the quantification of aneurysm pulsation is technically feasible and can be improved by computer-aided post-processing. MATERIALS AND
methodsImages of 14 cerebral aneurysms were acquired with an ECG-triggered 4D CTA. Aneurysms were post-processed manually and computer-aided on a 3D model. Volume curves and random noise-curves were compared with the arterial pulse wave and volume curves were compared between both post-processing modalities.
resultsThe aneurysm volume curves showed higher similarity with the pulse wave than the random curves (Hausdorff-distances 0.12 vs 0.25, p<0.01). Both post-processing methods did not differ in intra- (r = 0.45 vs r = 0.54, p>0.05) and inter-observer (r = 0.45 vs r = 0.54, p>0.05) reliability. Time needed for segmentation was significantly reduced in the computer-aided group (3.9 ± 1.8 min vs 20.8 ± 7.8 min, p<0.01).
conclusionOur results show pulsatile changes in a subset of the studied aneurysms with the final prove of underlying volume changes remaining unsettled. Semi-automatic post-processing significantly reduces post-processing time but cannot yet replace manual segmentation.
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