Evidence map›Paper›PMID 27879973›Full record

ArticleJournal for immunotherapy of cancer2016

Application of the Immunoscore as prognostic tool for hepatocellular carcinoma.

Annacarmen Petrizzo, Luigi Buonaguro

Abstract readEditorialComment
In one paragraph

Article in Journal for immunotherapy of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Necroptosis-driving genesJournal for immunotherapy of cancer · 2022
    Article
  6. A prognostic value of CD45RAScientific reports · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Annacarmen PetrizzoLaboratory of MolecularBiology and ViralOncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - IRCCS, Via Mariano Semmola, 1, 80131 Naples, Italy.
Luigi BuonaguroLaboratory of MolecularBiology and ViralOncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione Pascale" - IRCCS, Via Mariano Semmola, 1, 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, the American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC) tumor, nodes, metastasis (TNM) classification represents the standard system for evaluation of prognosis in solid tumors. However, the clinical outcome can be significantly different in patients with the same TNM stage. Therefore, many efforts have been made aiming to define new prognostic parameters. Indeed, analyses conducted in large cohorts of colorectal cancer patients emphasized the prognostic value of tumor-infiltrating lymphocytes, leading to the development of a prognostic score referred to as "Immunoscore". In this commentary, we recapitulate the study by Gabrielson and colleagues, recently published in Cancer Immunology Research, addressing the role of intratumoral CD3

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsB7-H1 AntigenBiomarkersHumansLymphocytes, Tumor-InfiltratingNeoplasm StagingPatient Outcome AssessmentPrognosisT-Lymphocyte SubsetsB7-H1 AntigenBiomarkersHepatocellular carcinomaImmunoscoreProgrammed Death Ligand 1 (PD-L1)TNM StageTumor-infiltrating lymphocytes

Identifiers

PMID27879973
PMCPMC5109780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.