Evidence map›Paper›PMID 27879921›Full record

ArticleSensors (Basel, Switzerland)2008

Laurate Biosensors Image Brain Neurotransmitters In Vivo: Can an Antihypertensive Medication Alter Psychostimulant Behavior?

Patricia A Broderick, Helen Ho, Karyn Wat, Vivek Murthy

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Patricia A BroderickDept.of Physiology and Pharmacology, The City University of New York (CUNY), USA. broderick@med.cuny.edu.
Helen HoDept.of Physiology and Pharmacology, The City University of New York (CUNY), USA.
Karyn WatDept.of Physiology and Pharmacology, The City University of New York (CUNY), USA.
Vivek MurthyDept.of Physiology and Pharmacology, The City University of New York (CUNY), USA.
City University of New York · US

Funding

VOLTAGE GATING OF ION CHANNELS--SIMULATIONS AND AB INITIO CALCULATIONSS06GM008168 · NIGMS · CITY COLLEGE OF NEW YORK · PI VENKATESH, TADMIRI RANGACHAR · 1989 to 2010
$17.6M
NIGMS NIH HHS S06 GM008168
6 · The paper itself

Abstract

Neuromolecular Imaging (NMI) with novel biosensors enables the selective detection of neurotransmitters in vivo within seconds, on line and in real time. Biosensors remain in place for continuing studies over a period of months. This biotechnological advance is based on conventional electrochemistry; the biosensors detect neurotransmitters by electron transfer. Simply stated, biosensors adsorb electrons from each neurotransmitter at specific oxidation potentials; the current derived from electron transfer is proportional to neurotransmitter concentration. Selective electron transfer properties of these biosensors permit the imaging of neurotransmitters, metabolites and precursors. The novel BRODERICK PROBE

Indexed as

anxietybraincaffeinecocainedopamineelectrochemistryG-protein receptor complexes (GPRC)homovanillic acidhypertensionketanserinL-tryptophanmesolimbicmotor tractsneuromolecular imagingnucleus accumbensopen-field behaviorspsychostimulantsserotoninventral tegmental area.

Identifiers

PMID27879921
PMCPMC3697160
OpenAlexW2161101069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.