Evidence map›Paper›PMID 27879681›Full record

ArticleMolecules (Basel, Switzerland)2016

Kuwanon G Preserves LPS-Induced Disruption of Gut Epithelial Barrier In Vitro.

Hengli Guo, Youhua Xu, Wei Huang, Hua Zhou, Zhaoguang Zheng, Yonghua Zhao, Bao He, Tingting Zhu, Shanshan Tang, Quan Zhu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  16. Mulberroside A from Cortex Mori Enhanced Gut Integrity in Diabetes.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  17. Prenylated phenolics as promising candidates for combination antibacterial therapy: Morusin and kuwanon G.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Hengli GuoFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. henry162037601@gmail.com.
Youhua XuFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. yhxu@must.edu.mo.
Wei HuangFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. huangwei1212520@163.com.
Hua ZhouFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. hzhou@must.edu.mo.
Zhaoguang ZhengInstitute of Consun Co. for Chinese Medicine in Kidney Diseases, Guangdong Consun Pharmaceutical Group, Dongpeng Road 71, Guangzhou 510760, China. dzhg168@126.com.
Yonghua ZhaoFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. yhzhao@must.edu.mo.
Bao HeInstitute of Consun Co. for Chinese Medicine in Kidney Diseases, Guangdong Consun Pharmaceutical Group, Dongpeng Road 71, Guangzhou 510760, China. hb_consun@163.com.
Tingting ZhuFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. zhulinke2012@163.com.
Shanshan TangFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. luckyshaniaya@vip.sina.com.
Quan ZhuFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao, China. 13570056996@163.com.
Macau University of Science and Technology · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Defects in the gut epithelial barrier have now been recognized to be responsible for diabetic endotoxemia. In everyday life, Mulberry leaf tea is widely used in Asian nations due to its proposed benefits to health and control of diabetes. Evidence indicates the potential role of Kuwanon G (KWG), a component from

Indexed as

Caco-2 CellsCell SurvivalCytokinesDose-Response Relationship, DrugEpithelial CellsFlavonoidsGene Expression RegulationHumansIntestinal MucosaLipopolysaccharidesMalondialdehydeReactive Oxygen SpeciesSuperoxide DismutaseTight Junction ProteinsTight JunctionsCytokinesFlavonoidskuwanon GLipopolysaccharidesMalondialdehydeReactive Oxygen SpeciesSuperoxide DismutaseTight Junction Proteinsdiabetes mellitusgut epithelial barrierinflammationKuwanon GMorus alba L.

Identifiers

PMID27879681
PMCPMC6272946
OpenAlexW2555364731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.