Evidence map›Paper›PMID 27879664›Full record

ArticleInternational journal of molecular sciences2016

Anti-Inflammatory Effects of Chloranthalactone B in LPS-Stimulated RAW264.7 Cells.

Xueqin Li, Jun Shen, Yunyao Jiang, Ting Shen, Long You, Xiaobo Sun, Xudong Xu, Weicheng Hu, Haifeng Wu, Gongcheng Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Frontiers in immunology · 2026
    Review
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  5. Review
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  8. Article
  9. 20-Hydroxy-3-Oxolupan-28-Oic Acid, a Minor Component FromFrontiers in bioengineering and biotechnology · 2021
    Article
  10. Article
  11. Anti-Inflammatory Potential ofEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  12. Article
  13. Immunomodulatory Effect of Flavonoids of Blueberry (Journal of immunology research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Xueqin LiDepartment of Gerontology, Huai'an First People's Hospital, Nanjing Medical University, Huaian 223300, China. doctorlixq@sina.com.
Jun ShenDepartment of Neurology, Huai'an Hospital Affiliated of Xuzhou Medical College and Huai'an Second People's Hospital, Huaian 223300, China. sj30918@163.com.
Yunyao JiangXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China. yunyao86@126.com.
Ting ShenJiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection, Huaiyin Normal University, Huaian 223300, China. shenting1019@163.com.
Long YouJiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection, Huaiyin Normal University, Huaian 223300, China. Long_YOU66@163.com.
Xiaobo SunKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. xbsun@implad.ac.cn.
Xudong XuKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. xdxu@implad.ac.cn.
Weicheng HuJiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection, Huaiyin Normal University, Huaian 223300, China. hu_weicheng@163.com.
Haifeng WuKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. hfwu@implad.ac.cn.
Gongcheng WangDepartment of Urology, Huai'an First People's Hospital, Nanjing Medical University, 6 Beijing West Road, Huaian 223300, China. wgc1955@sina.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNHuaiyin Normal University · CNHuaian First People’s Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chloranthalactone B (CTB), a lindenane-type sesquiterpenoid, was obtained from the Chinese medicinal herb

Indexed as

AnimalsAnti-Inflammatory AgentsCell LineCyclooxygenase 2DinoprostoneGene Expression RegulationInflammationInterleukin-1betaInterleukin-6JNK Mitogen-Activated Protein KinasesLactonesLipopolysaccharidesMacrophagesMAP Kinase Kinase 3MAP Kinase Kinase 6MiceAnti-Inflammatory Agentschloranthalactone BCyclooxygenase 2DinoprostoneIL1B protein, mouseInterleukin-1betaInterleukin-6interleukin-6, mouseJNK Mitogen-Activated Protein KinasesLactonesLipopolysaccharidesMap2k3 protein, mouseMap2k6 protein, mouseMAPK1 protein, humanMAP Kinase Kinase 3MAP Kinase Kinase 6Mitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Nitric OxideNitric Oxide Synthase Type IINos2 protein, mousep38 Mitogen-Activated Protein KinasesPtgs2 protein, mouseSesquiterpenesTranscription Factor AP-1Tumor Necrosis Factor-alphachloranthalactone BinflammationSarcandra glabrasesquiterpene

Identifiers

PMID27879664
PMCPMC5133933
OpenAlexW2557019421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.