Evidence map›Paper›PMID 27879317›Full record

ArticleThe Journal of biological chemistry2017

Correlated evolution between CK1δ Protein and the Serine-rich Motif Contributes to Regulating the Mammalian Circadian Clock.

Lijuan Xing, Yang An, Guangsen Shi, Jie Yan, Pancheng Xie, Zhipeng Qu, Zhihui Zhang, Zhiwei Liu, Dejing Pan, Ying Xu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. The CircadianInternational journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lijuan XingFrom the Cambridge-Suda Genomic Resource Center, Soochow University, 199 Renai Road, Suzhou 215123 and.
Yang Anthe MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 12 Xuefu Road, Pukou District, Nanjing 210061, China.
Guangsen ShiFrom the Cambridge-Suda Genomic Resource Center, Soochow University, 199 Renai Road, Suzhou 215123 and.
Jie YanFrom the Cambridge-Suda Genomic Resource Center, Soochow University, 199 Renai Road, Suzhou 215123 and.
Pancheng Xiethe MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 12 Xuefu Road, Pukou District, Nanjing 210061, China.
Zhipeng Quthe MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 12 Xuefu Road, Pukou District, Nanjing 210061, China.
Zhihui Zhangthe MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 12 Xuefu Road, Pukou District, Nanjing 210061, China.
Zhiwei LiuFrom the Cambridge-Suda Genomic Resource Center, Soochow University, 199 Renai Road, Suzhou 215123 and.
Dejing PanFrom the Cambridge-Suda Genomic Resource Center, Soochow University, 199 Renai Road, Suzhou 215123 and pandejing@suda.edu.cn.
Ying XuFrom the Cambridge-Suda Genomic Resource Center, Soochow University, 199 Renai Road, Suzhou 215123 and yingxu@suda.edu.cn.
Soochow University · CNModel Animal Research Center · CNNanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the mechanism underlying the physiological divergence of species is a long-standing issue in evolutionary biology. The circadian clock is a highly conserved system existing in almost all organisms that regulates a wide range of physiological and behavioral events to adapt to the day-night cycle. Here, the interactions between hCK1ϵ/δ/DBT (Drosophila ortholog of CK1δ/ϵ) and serine-rich (SR) motifs from hPER2 (ortholog of Drosophila per) were reconstructed in a Drosophila circadian system. The results indicated that in Drosophila, the SR mutant form hPER2

Indexed as

Evolution, MolecularAmino Acid SequenceAnimalsAnimals, Genetically ModifiedCasein Kinase 1 epsilonCircadian ClocksCLOCK ProteinsDrosophila melanogasterHumansMicePhenotypePhosphorylationPhylogenySequence Homology, Amino AcidSerineCasein Kinase 1 epsilonCLOCK ProteinsSerinecircadian clockcorrelated evolutionDrosophilainvertebratekinasemammalmouseorthologsphosphorylationsubstrates

Identifiers

PMID27879317
PMCPMC5217676
OpenAlexW2550314435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.