Evidence map›Paper›PMID 27879312›Full record

ArticleJournal of lipid research2017

Association of peripheral differential leukocyte counts with dyslipidemia risk in Chinese patients with hypertension: insight from the China Stroke Primary Prevention Trial.

Yanhong Liu, Xiangyi Kong, Wen Wang, Fangfang Fan, Yan Zhang, Min Zhao, Yi Wang, Yupeng Wang, Yu Wang, Xianhui Qin and 10 more

Abstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  17. Elevated White Blood Cell Count Resultant Atherogenesis is Associated With Panoramic-Imaged Carotid Plaque.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yanhong LiuSchool of Life Sciences, Anhui University, Hefei, China.
Xiangyi KongDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Wen WangInstitute for Biomedicine, Anhui Medical University, Hefei, China.
Fangfang FanDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Yan ZhangDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Min ZhaoNational Clinical Research Study Center for Kidney Disease, State Key Laboratory for Organ Failure Research, Renal Division, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yi WangDepartment of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Yupeng WangDepartment of Cardiology, Peking University Third Hospital, Beijing, China.
Yu WangNational Clinical Research Study Center for Kidney Disease, State Key Laboratory for Organ Failure Research, Renal Division, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xianhui QinNational Clinical Research Study Center for Kidney Disease, State Key Laboratory for Organ Failure Research, Renal Division, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Genfu TangInstitute for Biomedicine, Anhui Medical University, Hefei, China.
Binyan WangNational Clinical Research Study Center for Kidney Disease, State Key Laboratory for Organ Failure Research, Renal Division, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiping XuNational Clinical Research Study Center for Kidney Disease, State Key Laboratory for Organ Failure Research, Renal Division, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Fan Fan HouNational Clinical Research Study Center for Kidney Disease, State Key Laboratory for Organ Failure Research, Renal Division, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wei GaoDepartment of Cardiology, Peking University Third Hospital, Beijing, China.
Ningling SunDepartment of Cardiology, Peking University People's Hospital, Beijing, China.
Jianping LiDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Scott A VennersFaculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
Shanqun JiangSchool of Life Sciences, Anhui University, Hefei, China shanqunjiang2014@163.com huoyong@263.net.cn.
Yong HuoDepartment of Cardiology, Peking University First Hospital, Beijing, China shanqunjiang2014@163.com huoyong@263.net.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to examine the association between peripheral differential leukocyte counts and dyslipidemia in a Chinese hypertensive population. A total of 10,866 patients with hypertension were enrolled for a comprehensive assessment of cardiovascular risk factors using data from the China Stroke Primary Prevention Trial. Plasma lipid levels and total leukocyte, neutrophil, and lymphocyte counts were determined according to standard methods. Peripheral differential leukocyte counts were consistently and positively associated with serum total cholesterol (TC), LDL cholesterol (LDL-C), and TG levels (all P < 0.001 for trend), while inversely associated with HDL cholesterol levels (P < 0.05 for trend). In subsequent analyses where serum lipids were dichotomized (dyslipidemia/normolipidemia), we found that patients in the highest quartile of total leukocyte count (≥7.6 × 10

Indexed as

Leukocyte CountAgedCardiovascular DiseasesChinaCholesterolCholesterol, HDLCholesterol, LDLDyslipidemiasFemaleHumansHypertensionLipidsMaleMiddle AgedRisk FactorsTriglyceridesCholesterolCholesterol, HDLCholesterol, LDLLipidsTriglyceridesCSPPTepidemiologylymphocyteneutrophiltotal leukocyte

Identifiers

PMID27879312
PMCPMC5234728

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.