Evidence map›Paper›PMID 27877834›Full record

ArticleScience and technology of advanced materials2015

Encapsulation of palladium porphyrin photosensitizer in layered metal oxide nanoparticles for photodynamic therapy against skin melanoma.

Zih-An Chen, Yaswanth Kuthati, Ranjith Kumar Kankala, Yu-Chuan Chang, Chen-Lun Liu, Ching-Feng Weng, Chung-Yuan Mou, Chia-Hung Lee

Abstract read
In one paragraph

Article in Science and technology of advanced materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Photodynamic Therapy for Metastatic Melanoma Treatment: A Review.Technology in cancer research & treatment · 2018
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zih-An ChenDepartment of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, 974, Taiwan.
Yaswanth KuthatiDepartment of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, 974, Taiwan.
Ranjith Kumar KankalaDepartment of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, 974, Taiwan.
Yu-Chuan ChangDepartment of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, 974, Taiwan.
Chen-Lun LiuDepartment of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, 974, Taiwan.
Ching-Feng WengDepartment of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, 974, Taiwan.
Chung-Yuan MouDepartment of Chemistry, National Taiwan University, Taipei 10617, Taiwan.
Chia-Hung LeeDepartment of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, 974, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We designed a biodegradable nanocarrier of layered double hydroxide (LDH) for photodynamic therapy (PDT) based on the intercalation of a palladium porphyrin photosensitizer (PdTCPP) in the gallery of LDH for melanoma theragnosis. Physical and chemical characterizations have demonstrated the photosensitizer was stable in the layered structures. In addition, the synthesized nanocomposites rendered extremely efficacious therapy in the B16F10 melanoma cell line by improving the solubility of the hydrophobic PdTCPP photosensitizer. The detection of singlet oxygen generation under irradiation at the excitation wavelength of a 532 nm laser was indeed impressive. Furthermore, the

Indexed as

layered double hydroxidenanoparticlesphotodynamic therapy

Identifiers

PMID27877834
PMCPMC5070020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.