Evidence map›Paper›PMID 27877807›Full record

ArticleScience and technology of advanced materials2015

Effects of fluoridation of porcine hydroxyapatite on osteoblastic activity of human MG63 cells.

Zhipeng Li, Baoxin Huang, Sui Mai, Xiayi Wu, Hanqing Zhang, Wei Qiao, Xin Luo, Zhuofan Chen

Open access · goldAbstract read
In one paragraph

Article in Science and technology of advanced materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

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  8. Sintered fluorapatite scaffolds as an autograft-like engineered bone graft.Journal of biomedical materials research. Part B, Applied biomaterials · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Zhipeng LiGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Baoxin HuangGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Sui MaiGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Xiayi WuGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Hanqing ZhangGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Wei QiaoGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Xin LuoGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Zhuofan ChenGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, 56 LingYuan Road West, Guangzhou 510055, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Stomatology, 74 ZhongShan 2 Road, Guangzhou 510055, Guangdong, People's Republic of China.
Hospital of Stomatology, Sun Yat-sen UniversityStomatology Hospital · CNKey Laboratory of Guangdong Province · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological hydroxyapatite, derived from animal bones, is the most widely used bone substitute in orthopedic and dental treatments. Fluorine is the trace element involved in bone remodeling and has been confirmed to promote osteogenesis when administered at the appropriate dose. To take advantage of this knowledge, fluorinated porcine hydroxyapatite (FPHA) incorporating increasing levels of fluoride was derived from cancellous porcine bone through straightforward chemical and thermal treatments. Physiochemical characteristics, including crystalline phases, functional groups and dissolution behavior, were investigated on this novel FPHA. Human osteoblast-like MG63 cells were cultured on the FPHA to examine cell attachment, cytoskeleton, proliferation and osteoblastic differentiation for

Indexed as

biological hydroxyapatitefluoridationmaterial-cell interactionsosteoblastsporcine hydroxyapatite

Identifiers

PMID27877807
PMCPMC5099844
OpenAlexW637099734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.