Evidence map›Paper›PMID 27877592›Full record

ReviewScience and technology of advanced materials2013

Non-metallic nanomaterials in cancer theranostics: a review of silica- and carbon-based drug delivery systems.

Yu-Cheng Chen, Xin-Chun Huang, Yun-Ling Luo, Yung-Chen Chang, You-Zung Hsieh, Hsin-Yun Hsu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Science and technology of advanced materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu-Cheng ChenDepartment of Applied Chemistry and Institute of Molecular Science, National Chiao-Tung University, Tin-Ka-Pin Building R615B, No. 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan.
Xin-Chun HuangDepartment of Applied Chemistry and Institute of Molecular Science, National Chiao-Tung University, Tin-Ka-Pin Building R615B, No. 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan.
Yun-Ling LuoDepartment of Applied Chemistry and Institute of Molecular Science, National Chiao-Tung University, Tin-Ka-Pin Building R615B, No. 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan.
Yung-Chen ChangDepartment of Applied Chemistry and Institute of Molecular Science, National Chiao-Tung University, Tin-Ka-Pin Building R615B, No. 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan.
You-Zung HsiehDepartment of Applied Chemistry and Institute of Molecular Science, National Chiao-Tung University, Tin-Ka-Pin Building R615B, No. 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan.
Hsin-Yun HsuDepartment of Applied Chemistry and Institute of Molecular Science, National Chiao-Tung University, Tin-Ka-Pin Building R615B, No. 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan; Institute of Molecular Science, National Chiao-Tung University, No. 1001, Ta-Hsueh Road, Hsinchu 30010, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid development in nanomaterials has brought great opportunities to cancer theranostics, which aims to combine diagnostics and therapy for cancer treatment and thereby improve the healthcare of patients. In this review we focus on the recent progress of several cancer theranostic strategies using mesoporous silica nanoparticles and carbon-based nanomaterials. Silicon and carbon are both group IV elements; they have been the most abundant and significant non-metallic substances in human life. Their intrinsic physical/chemical properties are of critical importance in the fabrication of multifunctional drug delivery systems. Responsive nanocarriers constructed using these nanomaterials have been promising in cancer-specific theranostics during the past decade. In all cases, either a controlled texture or the chemical functionalization is coupled with adaptive properties, such as pH-, light-, redox- and magnetic field- triggered responses. Several studies in cells and mice models have implied their underlying therapeutic efficacy; however, detailed and long-term

Indexed as

carbon-based nanomaterialsdrug delivery systemsmesoporous silica nanoparticlestheranostics

Identifiers

PMID27877592
PMCPMC5090318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.