Evidence map›Paper›PMID 27877589›Full record

ArticleScience and technology of advanced materials2013

Paper-based tuberculosis diagnostic devices with colorimetric gold nanoparticles.

Tsung-Ting Tsai, Shu-Wei Shen, Chao-Min Cheng, Chien-Fu Chen

Abstract read
In one paragraph

Article in Science and technology of advanced materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Rapid Colorimetric Detection of Wound Infection with a Fluidic Paper Device.International journal of molecular sciences · 2022
    Article
  4. Article
  5. Nucleic Acids Analysis.Science China. Chemistry · 2021
    Review
  6. Colorimetric-based detection ofIET nanobiotechnology · 2020
    Article
  7. Article
  8. Paper-Based Sensors: Emerging Themes and Applications.Sensors (Basel, Switzerland) · 2018
    Review
  9. Article
  10. Cure of tuberculosis using nanotechnology: An overview.Journal of microbiology (Seoul, Korea) · 2018
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. On the Slow Diffusion of Point-of-Care Systems in Therapeutic Drug Monitoring.Frontiers in bioengineering and biotechnology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tsung-Ting TsaiDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital, Taipei 105, Taiwan; Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan 333, Taiwan.
Shu-Wei ShenGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
Chao-Min ChengInstitute of Nanoengineering and Microsystems, National Tsing Hua University, Hsinchu 300, Taiwan.
Chien-Fu ChenGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A colorimetric sensing strategy employing gold nanoparticles and a paper assay platform has been developed for tuberculosis diagnosis. Unmodified gold nanoparticles and single-stranded detection oligonucleotides are used to achieve rapid diagnosis without complicated and time-consuming thiolated or other surface-modified probe preparation processes. To eliminate the use of sophisticated equipment for data analysis, the color variance for multiple detection results was simultaneously collected and concentrated on cellulose paper with the data readout transmitted for cloud computing via a smartphone. The results show that the 2.6 nM tuberculosis mycobacterium target sequences extracted from patients can easily be detected, and the turnaround time after the human DNA is extracted from clinical samples was approximately 1 h.

Indexed as

colorimetric assaymicrofluidic paper-based analytical devicesTuberculosis diagnostics

Identifiers

PMID27877589
PMCPMC5090315

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.