Evidence map›Paper›PMID 27877236›Full record

ArticleTheranostics2016

Core-Shell Nanostars for Multimodal Therapy and Imaging.

Mengyuan Li, Lele Li, Changyou Zhan, Daniel S Kohane

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  3. Article
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  9. Review
  10. Molecular Imaging in Nanotechnology and Theranostics.Molecular imaging and biology · 2017
    Review
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mengyuan LiLaboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, 02115. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA 02139, USA.
Lele LiLaboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, 02115. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA 02139, USA.
Changyou ZhanLaboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, 02115. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA 02139, USA.
Daniel S KohaneLaboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Division of Critical Care Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, 02115. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA 02139, USA.

Funding

Prolonged Duration Local AnesthesiaR01GM073626 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI KOHANE, DANIEL S · 2006 to 2018
$4.7M
NIGMS NIH HHS R01 GM073626
6 · The paper itself

Abstract

The coupling of diagnostic capability and effective therapy in a single multifunctional nanomedicine is desirable but remains challenging. Here, we developed multifunctional nanoparticles consisting of a gold nanostar (AuNS) core with a shell of metal-drug coordination polymer (CP). The AuNS core enabled plasmonic photothermal effect and two-photon photoluminescence (TPL), while the CP shell of gadolinium and gemcitabine monophosphate allowed chemotherapy and MRI imaging. The AuNS@CP nanoparticles exhibited a strong

Indexed as

AnimalsBreast NeoplasmsCombined Modality TherapyDiagnostic Tests, RoutineDisease Models, AnimalDrug CarriersDrug TherapyGoldHyperthermia, InducedNanoparticlesOptical ImagingPhotochemotherapyTheranostic NanomedicineTransplantation, HeterologousTreatment OutcomeDrug CarriersGoldgold nanostarimaging

Identifiers

PMID27877236
PMCPMC5118596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.