Evidence map›Paper›PMID 27877174›Full record

ArticleFrontiers in immunology2016

DNA Methyltransferase Inhibitor Promotes Human CD4

Chun-Hao Lu, Cheng-Jang Wu, Cheng-Chi Chan, Duc T Nguyen, Kuo-Ray Lin, Syh-Jae Lin, Li-Chen Chen, Jeffrey Jong-Yong Yen, Ming-Ling Kuo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Epigenetic modification of CD4Cell death & disease · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis.Oxidative medicine and cellular longevity · 2022
    Article
  11. Review
  12. Regulatory T Cells-Related Genes Are under DNA Methylation Influence.International journal of molecular sciences · 2021
    Review
  13. Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Chun-Hao LuDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University , Taoyuan , Taiwan.
Cheng-Jang WuDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.
Cheng-Chi ChanDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University , Taoyuan , Taiwan.
Duc T NguyenDivision of Biological Sciences, University of California San Diego , La Jolla, CA , USA.
Kuo-Ray LinInstitute of Biomedical Sciences, Academia Sinica , Taipei , Taiwan.
Syh-Jae LinDepartment of Pediatrics, Division of Allergy, Asthma, and Rheumatology, Chang Gung Memorial Hospital , Taoyuan , Taiwan.
Li-Chen ChenDepartment of Pediatrics, Division of Allergy, Asthma, and Rheumatology, Chang Gung Memorial Hospital , Taoyuan , Taiwan.
Jeffrey Jong-Yong YenInstitute of Biomedical Sciences, Academia Sinica , Taipei , Taiwan.
Ming-Ling KuoDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Pediatrics, Division of Allergy, Asthma, and Rheumatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung Immunology Consortium, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
Chang Gung University · TWChang Gung Memorial Hospital · TWInstitute of Biomedical Sciences, Academia Sinica · TWUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The "master transcription factor" FOXP3 regulates the differentiation, homeostasis, and suppressor function of CD4

Indexed as

epigenetic regulationFOXP3human regulatory T cellimmunological tolerancesuboptimal TCR stimulation

Identifiers

PMID27877174
PMCPMC5099256
OpenAlexW2549871869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.