Evidence map›Paper›PMID 27877082›Full record

ArticleInternational journal of biological sciences2016

Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation.

Zhantao Deng, Xiaozhou Liu, Jiewen Jin, Haidong Xu, Qian Gao, Yong Wang, Jianning Zhao

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Systematic Analysis of theInternational journal of molecular sciences · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Osteosarcoma mechanobiology and therapeutic targets.British journal of pharmacology · 2022
    Review
  12. Article
  13. The Histone Deacetylase Inhibitor Entinostat/Syndax 275 in Osteosarcoma.Advances in experimental medicine and biology · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhantao DengDepartment of Orthopedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China.; Center for Translational Medicine, Nanjing University Medical School, Nanjing, Jiangsu, PR China.; Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, PR China.
Xiaozhou LiuDepartment of Orthopedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China.
Jiewen JinCenter for Translational Medicine, Nanjing University Medical School, Nanjing, Jiangsu, PR China.; Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, PR China.
Haidong XuDepartment of Orthopedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China.
Qian GaoCenter for Translational Medicine, Nanjing University Medical School, Nanjing, Jiangsu, PR China.; Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, PR China.
Yong WangCenter for Translational Medicine, Nanjing University Medical School, Nanjing, Jiangsu, PR China.; Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, PR China.
Jianning ZhaoDepartment of Orthopedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China.
Nanjing General Hospital of Nanjing Military Command · CNNanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisBlotting, WesternCell CycleCell Line, TumorCell ProliferationFlow CytometryHistone AcetyltransferasesHistone Deacetylase InhibitorsHistone DeacetylasesHumansHydroxamic AcidsIn Vitro TechniquesOsteosarcomaSignal TransductionTumor Suppressor Protein p53Histone AcetyltransferasesHistone Deacetylase InhibitorsHistone DeacetylasesHydroxamic Acidstrichostatin ATumor Suppressor Protein p53apoptosisHDACosteosarcomap53Trichostatin A

Identifiers

PMID27877082
PMCPMC5118776
OpenAlexW2552357345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.