ArticleScientific reports2016
The measurement of lung volumes using body plethysmography and helium dilution methods in COPD patients: a correlation and diagnosis analysis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Diffusing capacity in chronic obstructive pulmonary disease assessment: A meta-analysis.Chronic respiratory diseasePooled it
- Lung Function-Based Assessment of Small Airway Dysfunction in Chronic Respiratory Diseases.Biology · 2026Review
- The Effectiveness of Home-Based Inspiratory Muscle Training on Small Airway Function and Disease-Associated Symptoms in Patients with Chronic Obstructive Pulmonary Disease.Healthcare (Basel, Switzerland) · 2023Article
- Predicting total lung capacity from spirometry: a machine learning approach.Frontiers in medicine · 2023Article
- Deep learning using multilayer perception improves the diagnostic acumen of spirometry: a single-centre Canadian study.BMJ open respiratory research · 2022Article
- Factors affecting complications development and mortality after single lung transplant.World journal of transplantation · 2021Review
- Multiple breath washout testing in adults with pulmonary disease and healthy controls - can fewer measurements eventually be more?BMC pulmonary medicine · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease (COPD) is a chronic airway disease characterized by persistent airflow limitation. Moreover, lung hyperinflation evaluated by lung volumes is also the key pathophysiologic process during COPD progression. Nevertheless, there is still no preferred method to evaluate lung volumes. For this study, we recruited 170 patients with stable COPD to assess lung volumes stratified by airflow limitation severity. Lung volumes including residual volume (RV) and total lung capacity (TLC) were determined by both body plethysmography and helium dilution methods. The discrepancies between these two methods were recorded as ΔRV%pred, ΔTLC%pred, and ΔRV/TLC. We found that ΔRV%pred, ΔTLC%pred, and ΔRV/TLC increased significantly with the severity of COPD. The differences of lung capacity between these two methods were negatively correlated with FEV
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Registered trials
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