ArticleNature communications2016
Proliferation of Listeria monocytogenes L-form cells by formation of internal and external vesicles.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 60 citations in OpenAlex.
- Flip Flop-Associated Growth and Division of Synthetic Cells.ACS nano · 2026Article
- Bacterial L-forms: Key Mechanisms of Drug Resistance, Disease Recurrence, and Immune Evasion.Indian journal of microbiology · 2026Review
- The Flavonoids Daidzein and Genistein Induce Wall-Deficient Cell Formation in Streptomyces coelicolor Under Hyperosmotic Stress.Microbial biotechnology · 2026Article
- Deep-learning deconvolution and segmentation of fluorescent membranes for high-precision bacterial cell-size profiling.Communications biology · 2026Article
- High-quality draft genome of the Listeria monocytogenes, one more vaccine strain against livestock listeriosis.Scientific data · 2026Article
- Synergistic action of peptidoglycan and teichoic acid synthesis inhibitors leads to cell death by oxidative damage.Communications biology · 2026Article
- Revealing Cell Envelope Heterogeneity in Two StableInternational journal of molecular sciences · 2026Article
- Engineering bacterial cell morphology for the design of robust cell factories.Biochemistry and biophysics reports · 2025Review
- Disruption of salt bridge interactions in the inter-domain cleft of the tubulin-like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723.Cytoskeleton (Hoboken, N.J.) · 2025Article
- Synergistic Enzybiotic Effect of a Bacteriophage Endolysin and an Engineered Glucose Oxidase AgainstBiomolecules · 2024Article
- A tuneable minimal cell membrane reveals that two lipid species suffice for life.Nature communications · 2024Article
- A tuneable minimal cell membrane reveals that two lipid species suffice for life.bioRxiv : the preprint server for biology · 2024Article
- The reproduction process of Gram-positive protocells.Scientific reports · 2024Article
- The reproduction of gram-negative protoplasts and the influence of environmental conditions on this process.iScience · 2023Article
- Comparative genomics hints at dispensability of multiple essential genes in two Escherichia coli L-form strains.Bioscience reports · 2023Article
- Open Questions about the Roles of DnaA, Related Proteins, and Hyperstructure Dynamics in the Cell Cycle.Life (Basel, Switzerland) · 2023Review
- Bacteria can shed a layer when phages turn up the heat.Nature microbiology · 2023Article
- L-form conversion in Gram-positive bacteria enables escape from phage infection.Nature microbiology · 2023Article
- Dissipative Particle Dynamics Simulations for Shape Change of Growing Lipid Bilayer Vesicles.Life (Basel, Switzerland) · 2023Article
- Advance on Engineering of Bacteriophages by Synthetic Biology.Infection and drug resistance · 2023Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
L-forms are cell wall-deficient bacteria that divide through unusual mechanisms, involving dynamic perturbations of the cellular shape and generation of vesicles, independently of the cell-division protein FtsZ. Here we describe FtsZ-independent mechanisms, involving internal and external vesicles, by which Listeria monocytogenes L-forms proliferate. Using micromanipulation of single cells and vesicles, we show that small vesicles are formed by invagination within larger intracellular vesicles, receive cytoplasmic content, and represent viable progeny. In addition, the L-forms can reproduce by pearling, that is, generation of extracellular vesicles that remain transiently linked to their mother cell via elastic membranous tubes. Using photobleaching and fluorescence recovery, we demonstrate cytoplasmic continuity and transfer through these membranous tubes. Our findings indicate that L-forms' polyploidy and extended interconnectivity through membranous tubes contribute to the generation of viable progeny independently of dedicated division machinery, and further support L-forms as models for studies of potential multiplication mechanisms of hypothetical primitive cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.