Evidence map›Paper›PMID 27876448›Full record

ReviewNanomedicine (London, England)2017

Magnetic nanoparticles for precision oncology: theranostic magnetic iron oxide nanoparticles for image-guided and targeted cancer therapy.

Lei Zhu, Zhiyang Zhou, Hui Mao, Lily Yang

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed.

  1. Review
  2. Review
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  5. Review
  6. Article
  7. Molecules (Basel, Switzerland) · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. On the lifespan ofAging · 2024
    Article
  13. Article
  14. Recent Insights into Nanotechnology in Colorectal Cancer.Applied biochemistry and biotechnology · 2024
    Review
  15. Molecules (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Metal-based nanoparticle in cancer treatment: lessons learned and challenges.Frontiers in bioengineering and biotechnology · 2024
    Review

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei ZhuDepartments of Surgery & Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
Zhiyang ZhouDepartments of Surgery & Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
Hui MaoDepartments of Surgery & Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
Lily YangDepartments of Surgery & Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.

Funding

Stroma Breaking Theranostic Nanoparticle for Targeted Pancreatic Cancer TherapyU01CA198913 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2015 to 2019
$3.0M
Theranostic Nano particles for Targeted Treatment of Pancreatic CancerU01CA151810 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2010 to 2014
$2.2M
MRI Capable Receptor Targeted Drug Delivery for Pancreatic CancerR01CA154846 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2011 to 2015
$2.1M
Targeted Therapy of Triple Negative Breast Cancer Using Theranostic NanoparticlesR01CA154129 · NCI · EMORY UNIVERSITY · PI YANG, LILY · 2011 to 2015
$1.7M
NCI NIH HHS R01 CA154129NCI NIH HHS R01 CA154846NCI NIH HHS U01 CA151810NCI NIH HHS U01 CA198913
6 · The paper itself

Abstract

Recent advances in the development of magnetic nanoparticles (MNPs) have shown promise in the development of new personalized therapeutic approaches for clinical management of cancer patients. The unique physicochemical properties of MNPs endow them with novel multifunctional capabilities for imaging, drug delivery and therapy, which are referred to as theranostics. To facilitate the translation of those theranostic MNPs into clinical applications, extensive efforts have been made on designing and improving biocompatibility, stability, safety, drug-loading ability, targeted delivery, imaging signal and thermal- or photodynamic response. In this review, we provide an overview of the physicochemical properties, toxicity and theranostic applications of MNPs with a focus on magnetic iron oxide nanoparticles.

Indexed as

Contrast MediaFerric CompoundsMagnetite NanoparticlesTheranostic NanomedicineAnimalsAntineoplastic AgentsDrug Delivery SystemsHumansMagnetic Resonance ImagingNeoplasmsPrecision MedicineSurface PropertiesAntineoplastic AgentsContrast MediaFerric Compoundsferric oxideMagnetite Nanoparticlesiron oxide nanoparticlemagnetic nanoparticlestheranostic

Identifiers

PMID27876448
PMCPMC5144490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.