Evidence map›Paper›PMID 27876407›Full record

ArticleThe Journal of investigative dermatology2017

Complement C3 Exacerbates Imiquimod-Induced Skin Inflammation and Psoriasiform Dermatitis.

Chiara Giacomassi, Norzawani Buang, Guang Sheng Ling, Greg Crawford, H Terence Cook, Diane Scott, Francesco Dazzi, Jessica Strid, Marina Botto

Open access · hybridAbstract readLetter
In one paragraph

Article in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Modular complement assemblies for mitigating inflammatory conditions.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. C3 Drives Inflammatory Skin Carcinogenesis Independently of C5.The Journal of investigative dermatology · 2021
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chiara GiacomassiCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK.
Norzawani BuangCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK.
Guang Sheng LingCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK.
Greg CrawfordCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK.
H Terence CookCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK.
Diane ScottCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK.
Francesco DazziHaemato-Oncology Department, King's College London, UK.
Jessica StridCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK.
Marina BottoCentre for Complement and Inflammation Research, Department of Medicine, Imperial College London, London, UK. Electronic address: m.botto@imperial.ac.uk.
Centre for Inflammation Research · GBImperial College London · GBKing's College London · GB

Funding

Medical Research Council MR/L022699/1Wellcome Trust 108008/Z/15/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Complement ActivationDermatitisImmunity, CellularSkinAdjuvants, ImmunologicAminoquinolinesComplement C3HumansImiquimodAdjuvants, ImmunologicAminoquinolinesC3 protein, humanComplement C3Imiquimod

Identifiers

PMID27876407
PMCPMC5319416
OpenAlexW2549865073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.