Evidence map›Paper›PMID 27876151›Full record

ArticleThe American journal of pathology2016

Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice.

Rakesh H Basavalingappa, Chandirasegaran Massilamany, Bharathi Krishnan, Arunakumar Gangaplara, Guobin Kang, Vahid Khalilzad-Sharghi, Zhongji Han, Shadi Othman, Qingsheng Li, Jean-Jack Riethoven and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

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  15. β1-Adrenergic Receptor Contains Multiple IAFrontiers in immunology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rakesh H BasavalingappaSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Chandirasegaran MassilamanySchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Bharathi KrishnanSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Arunakumar GangaplaraSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Guobin KangNebraska Center for Virology and School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Vahid Khalilzad-SharghiDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska.
Zhongji HanDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska.
Shadi OthmanDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska.
Qingsheng LiNebraska Center for Virology and School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Jean-Jack RiethovenCenter for Biotechnology, University of Nebraska-Lincoln, Lincoln, Nebraska.
Raymond A SobelDepartment of Pathology, Stanford University School of Medicine, Stanford, California.
David SteffenSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Jay ReddySchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska. Electronic address: nreddy2@unl.edu.
University of Nebraska–Lincoln · USStanford University · US

Funding

The role of stress in the fetal origin of obesity and metabolic dysfunctionP20GM104320 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI ZEMPLENI, JANOS · 2014 to 2024
$24.9M
Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
Autoimmunity in the Mediation of Infectious MyocarditisR01HL114669 · NHLBI · UNIVERSITY OF NEBRASKA LINCOLN · PI REDDY, JAY · 2013 to 2016
$1.4M
NHLBI NIH HHS R01 HL114669NIGMS NIH HHS P20 GM104320NIGMS NIH HHS P30 GM103509
6 · The paper itself

Abstract

Heart failure, a leading cause of death in humans, can emanate from myocarditis. Although most individuals with myocarditis recover spontaneously, some develop chronic dilated cardiomyopathy. Myocarditis may result from both infectious and noninfectious causes, including autoimmune responses to cardiac antigens. In support of this notion, intracellular cardiac antigens, like cardiac myosin heavy chain-α, cardiac troponin-I, and adenine nucleotide translocator 1 (ANT

Indexed as

Adenine Nucleotide Translocator 1AnimalsAutoantigensCardiac MyosinsCardiomyopathy, DilatedEpitopesFemaleHeartHumansInflammationInterleukin-17MiceMitochondrial ProteinsMyocarditisT-LymphocytesTroponin IAdenine Nucleotide Translocator 1AutoantigensCardiac MyosinsEpitopesInterleukin-17Mitochondrial ProteinsTroponin I

Identifiers

PMID27876151
PMCPMC5225289
OpenAlexW2549096308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.