ArticleBMC research notes2016
Onychomycosis in diabetic patients in Fako Division of Cameroon: prevalence, causative agents, associated factors and antifungal sensitivity patterns.
Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 46 citations in OpenAlex.
- An Overview of the Treatment of Onychomycosis in Patients with Diabetes: Current Pharmacological and Non-Pharmacological Options.Clinical, cosmetic and investigational dermatology · 2026Review
- Onychomycosis in Diabetics: A Common Infection with Potentially Serious Complications.Life (Basel, Switzerland) · 2025Review
- Onychomycosis Endonyx: A Systematic Review.Diseases (Basel, Switzerland) · 2025Review
- Lipid-based nanoformulations in onychomycosis therapy: addressing challenges of current therapies and advancing treatment.RSC advances · 2025Review
- Prevalence and Risk Factors Predicting Onychomycosis in Patients with and Without Diabetes Mellitus in Spain: A Cross-Sectional Study.Journal of fungi (Basel, Switzerland) · 2024Article
- Review
- Clinical and epidemiological study of onychomycosis among patients of the national institute of hygiene in rabat, Morocco (2016-2020).Current medical mycology · 2023Article
- Onychomycosis in Patients with Diabetes Mellitus in Africa: A Global Scoping Review, 2000-2021.Mycopathologia · 2023Article
- Metagenomics of Toenail Onychomycosis in Three Victorian Regions of Australia.Journal of fungi (Basel, Switzerland) · 2022Article
- Luliconazole Nail Lacquer for the Treatment of Onychomycosis: Formulation, Characterization and In Vitro and Ex Vivo Evaluation.AAPS PharmSciTech · 2022Article
- Correlation of clinical characteristics, by calculation of SCIO index, with the laboratory diagnosis of onychomycosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Onychomycosis in Psoriatic Patients with Nail Disorders: Aetiological Agents and Immunosuppressive Therapy.Dermatology research and practice · 2020Article
- Challenges and Opportunities in the Management of Onychomycosis.Journal of fungi (Basel, Switzerland) · 2018Review
- The Burden of Serious Fungal Infections in Cameroon.Journal of fungi (Basel, Switzerland) · 2018Article
- Clinico-Mycological Study of Onychomycosis in Indian Diabetic Patients.Indian dermatology online journalArticle
- Foot Health Assessment and Problem Identification in a Dominican Batey Community: A Descriptive Study.Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses SocietyArticle
- Antifungal Drug Susceptibility Testing of Dermatophytes: Laboratory Findings to Clinical Implications.Indian dermatology online journalArticle
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOnychomycosis is an infection of the nail unit by a fungus. This is a very common infection amongst diabetics. Its occurrence among diabetics in Fako division is unknown. In this study we provide information on the characteristics of onychomycosis in diabetics in Fako division, Cameroon.
methodsA cross-sectional descriptive and analytical hospital-based study was conducted in two diabetic clinics in the Buea and Limbe regional hospitals. We recruited 152 consenting diabetics into the study. Demographic, behavioural, and clinical data of patients were obtained through the use of structured questionnaires. Toenail, finger nail, skin scrapings and nail clippings were collected from participants, KOH mounts were prepared and observed under the microscope and cultured on Sabouraud Dextrose Agar supplemented with chloramphenicol to isolate causative fungi. Identification of isolates was done to species level using the cello tape flag method and slide culture. The presence of a dermatophyte by either microscopy or culture or both methods was considered positive for onychomycosis. Antifungal susceptibility testing was carried out using selected antifungals by the Kirby-Bauer disk diffusion method on Sabouraud Dextrose Agar.
resultsClinical onychomycosis was found in 77 of the 152 diabetics tested giving a prevalence of 50.7% (95% CI 42.4-58.9) in diabetics in Fako. No socio-demographic or clinical factor studied was significantly associated with onychomycosis. Trichophyton rubrum was the most common isolate (62%). Other isolates included Trichophyton metagraphyte (22%) and Trichophyton tonsurans (16%). Dermatophytes were sensitive to miconazole (66%), amphotericin B (19%) and ketoconazole (14%).
conclusionOnychomycosis is common in diabetics in Fako signifying the need for regular screening by either microscopy or culture. Infected nails could be treated with miconazole.
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