ArticleParasites & vectors2016
In vitro activity of ten essential oils against Sarcoptes scabiei.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 70 citations in OpenAlex.
- Integrated in vitro and in vivo evaluation of ivermectin hydrogel formulation for management of scabies with pharmacological assessment.Scientific reports · 2026Article
- Phytomedicines and conventional drugs in scabies management.GMS hygiene and infection control · 2026Review
- Investigating the potential scabicidal activities of three essential oils: gaining mechanistic insights through in vitro contact bioassay and molecular docking.BMC complementary medicine and therapies · 2025Article
- Antiparasitic efficacy of geraniol from Apiaceae family in scabies treatment.Scientific reports · 2025Article
- Antioxidant Potential of Medicinal Plants in the Treatment of Scabies Infestation.Molecules (Basel, Switzerland) · 2024Review
- Assessment of the in vitro acaricidal activity of BravectoParasites & vectors · 2024Article
- Effects of essential oils on economically important characteristics of ruminant species: A comprehensive review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Essential oil pharmaceuticals for killing ectoparasites on dogs.Journal of veterinary science · 2024Article
- Natural Products as Mite Control Agents in Animals: A Review.Molecules (Basel, Switzerland) · 2023Review
- Egyptian mandarin peel oil's anti-scabies potential via downregulation-of-inflammatory/immune-cross-talk: GC-MS and PPI network studies.Scientific reports · 2023Article
- Can Ivermectin kill Sarcoptes scabiei during the molting process?PLoS neglected tropical diseases · 2023Article
- In Vitro Efficacy of Terpenes from Essential Oils againstMolecules (Basel, Switzerland) · 2023Article
- Comparison of in vitro Killing Effect of Thai Herbal Essential Oils, Tea Tree Oil, and Metronidazole 0.75% versus Ivermectin 1% onClinical, cosmetic and investigational dermatology · 2023Article
- Essential Oils againstMolecules (Basel, Switzerland) · 2022Review
- Investigating the Antibacterial Properties of Prospective Scabicides.Biomedicines · 2022Article
- The Efficacy and Biopharmaceutical Properties of a Fixed-Dose Combination of Disulfiram and Benzyl Benzoate.International journal of molecular sciences · 2022Article
- Antiparasitic Activity of Tea Tree Oil (TTO) and Its Components against Medically Important Ectoparasites: A Systematic Review.Pharmaceutics · 2022Review
- In vitro efficacy of essential oils against Sarcoptes scabiei.Scientific reports · 2022Article
- The Effects of Commercially AvailableInfection and drug resistance · 2022Article
- Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe development of alternative approaches in ectoparasite management is currently required. Essential oils have been demonstrated to exhibit fumigant and topical toxicity to a number of arthropods. The aim of the present study was to assess the potential efficacy of ten essential oils against Sarcoptes scabiei.
methodsThe major chemical components of the oils were identified by GC-MS analysis. Contact and fumigation bioassays were performed on Sarcoptes mites collected from experimentally infected pigs. For contact bioassays, essential oils were diluted with paraffin to get concentrations at 10, 5, and even 1% for the most efficient ones. The mites were inspected under a stereomicroscope 10, 20, 30, 40, 50, 60, 90, 120, 150, and 180min after contact. For fumigation bioassay, a filter paper was treated with 100 μL of the pure essential oil. The mites were inspected under a stereomicroscope for the first 5min, and then every 5min until 1h.
resultsUsing contact bioassays, 1% clove and palmarosa oil killed all the mites within 20 and 50min, respectively. The oils efficacy order was: clove > palmarosa > geranium > tea tree > lavender > manuka > bitter orange > eucalyptus > Japanese cedar. In fumigation bioassays, the efficacy order was: tea tree > clove > eucalyptus > lavender > palmarosa > geranium > Japanese cedar > bitter orange > manuka. In both bioassays, cade oil showed no activity.
conclusionEssential oils, especially tea tree, clove, palmarosa, and eucalyptus oils, are potential complementary or alternative products to treat S. scabiei infections in humans or animals, as well as to control the mites in the environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.