ArticleMalaria journal2016
Increasing insecticide resistance in Anopheles funestus and Anopheles arabiensis in Malawi, 2011-2015.
Article in Malaria journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trends in insecticide resistance in Anopheles mosquitoes (Diptera: Culicidae) in Ghana: a systematic review.Journal of medical entomology · 2025Pooled it
- Assessment of the effect of larval source management and house improvement on malaria transmission when added to standard malaria control strategies in southern Malawi: study protocol for a cluster-randomised controlled trial.BMC infectious diseases · 2017Trial
- Less is more: modelling the impact of species-targeted versus broadcast larviciding in Anopheles funestus-dominated malaria transmission settings.Malaria journal · 2026Article
- Insecticide resistance profiles of Anopheles arabiensis and relationship with Microsporidia MB infection in two rice agroecosystems in Kenya.Parasites & vectors · 2026Article
- A large-scale mosquito larviciding in Tanga Region, Tanzania, reduced mosquito densities to varying degrees across malaria transmission risk strata.Scientific reports · 2025Article
- The Effectiveness of Indoor Residual Spraying for Malaria Control in Sub-Saharan Africa: A Systematic Protocol Review and Meta-Analysis.International journal of environmental research and public health · 2025Article
- Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.medRxiv : the preprint server for health sciences · 2024Article
- Dynamics of malaria vector composition and Plasmodium falciparum infection in mainland Tanzania: 2017-2021 data from the national malaria vector entomological surveillance.Malaria journal · 2024Article
- Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.PLOS global public health · 2024Article
- Article
- Changes in contributions of different Anopheles vector species to malaria transmission in east and southern Africa from 2000 to 2022.Parasites & vectors · 2023Review
- Barriers to accessing malaria treatment amongst school-age children in rural Malawi.Malaria journal · 2023Article
- Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi.Malaria journal · 2023Article
- Trends of insecticide resistance monitoring in mainland Tanzania, 2004-2020.Malaria journal · 2023Article
- Measuring entomological parameters before implementing a study on asymptomatic carriers of Plasmodium falciparum in the Zè District in southern Benin.Malaria journal · 2023Article
- Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi.Malaria journal · 2023Article
- Seasonal variation in abundance and blood meal sources of primary and secondary malaria vectors within Kilombero Valley, Southern Tanzania.Parasites & vectors · 2022Article
- Potential of Essential Oil-Based Anticholinesterase Insecticides againstMolecules (Basel, Switzerland) · 2022Review
- Malawi ICEMR Malaria Research: Interactions and Results Influencing Health Policies and Practices.The American journal of tropical medicine and hygiene · 2022Article
- Understanding the Intransigence of Malaria in Malawi.The American journal of tropical medicine and hygiene · 2022Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
backgroundSusceptibility of principal Anopheles malaria vectors to common insecticides was monitored over a 5-year period across Malawi to inform and guide the national malaria control programme.
methodsAdult blood-fed Anopheles spp. and larvae were collected from multiple sites in sixteen districts across the country between 2011 and 2015. First generation (F
resultsMortality of Anopheles funestus to deltamethrin, permethrin, bendiocarb and propoxur declined significantly over the 5-year (2011-2015) monitoring period. There was wide variation in susceptibility to DDT but it was not associated with time. In contrast, An. funestus exhibited 100% mortality to the organophosphates (malathion and pirimiphos-methyl) at all sites tested. There was reduced mortality of Anopheles arabiensis to deltamethrin over time though this was not statistically significant. However, mortality of An. arabiensis exposed to permethrin declined significantly over time. Anopheles arabiensis exposed to DDT were more likely to be killed if there was high ITN coverage in the mosquito collection area the previous year. There were no other associations between mosquito mortality in a bioassay and ITN coverage or IRS implementation. Mortality of An. funestus from four sites exposed to deltamethrin alone ranged from 2 to 31% and from 41 to 94% when pre-exposed to the synergist piperonyl butoxide followed by deltamethrin. For permethrin alone, mortality ranged from 2 to 13% while mortality ranged from 63 to 100% when pre-exposed to PBO.
conclusionPyrethroid resistance was detected in An. funestus and An. arabiensis populations across Malawi and has worsened over the last 5 years. New insecticides and control strategies are urgently needed to reduce the burden of malaria in Malawi.
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