Trial reportPloS one2016
Spatio-Temporal Progression of Cortical Activity Related to Continuous Overt and Covert Speech Production in a Reading Task.
Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 71 citations in OpenAlex.
- Towards an understanding of somatosensory perturbation on covert speech production: a functional near infrared spectroscopy study.Frontiers in human neuroscience · 2026Article
- Revealing spatiotemporal neural activation patterns in electrocorticography recordings of human speech production by mutual information.Neuroscience informatics · 2025Article
- Learning to operate an imagined speech Brain-Computer Interface involves the spatial and frequency tuning of neural activity.Communications biology · 2025Article
- Decoding Single and Paired Phonemes Using 7T Functional MRI.Brain topography · 2024Article
- Imagined speech event detection from electrocorticography and its transfer between speech modes and subjects.Communications biology · 2024Article
- Adaptive LDA Classifier Enhances Real-Time Control of an EEG Brain-Computer Interface for Decoding Imagined Syllables.Brain sciences · 2024Article
- Bipolar and Laplacian montages are suitable for high-gamma modulation language mapping with stereoelectroencephalography.Frontiers in neurology · 2024Article
- Decoding and synthesizing tonal language speech from brain activity.Science advances · 2023Article
- Aberrant neurophysiological signaling associated with speech impairments in Parkinson's disease.NPJ Parkinson's disease · 2023Article
- Recommendations for promoting user agency in the design of speech neuroprostheses.Frontiers in human neuroscience · 2023Article
- Neural representation of phonological information during Chinese character reading.Human brain mapping · 2022Article
- 2020 International brain-computer interface competition: A review.Frontiers in human neuroscience · 2022Review
- Modulation in cortical excitability disrupts information transfer in perceptual-level stimulus processing.NeuroImage · 2021Article
- Real-time synthesis of imagined speech processes from minimally invasive recordings of neural activity.Communications biology · 2021Article
- Multiclass covert speech classification using extreme learning machine.Biomedical engineering letters · 2020Article
- NeuroVAD: Real-Time Voice Activity Detection from Non-Invasive Neuromagnetic Signals.Sensors (Basel, Switzerland) · 2020Article
- Electrocorticography reveals spatiotemporal neuronal activation patterns of verbal fluency in patients with epilepsy.Neuropsychologia · 2020Article
- Effortful verb retrieval from semantic memory drives beta suppression in mesial frontal regions involved in action initiation.Human brain mapping · 2019Article
- Speech synthesis from ECoG using densely connected 3D convolutional neural networks.Journal of neural engineering · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
How the human brain plans, executes, and monitors continuous and fluent speech has remained largely elusive. For example, previous research has defined the cortical locations most important for different aspects of speech function, but has not yet yielded a definition of the temporal progression of involvement of those locations as speech progresses either overtly or covertly. In this paper, we uncovered the spatio-temporal evolution of neuronal population-level activity related to continuous overt speech, and identified those locations that shared activity characteristics across overt and covert speech. Specifically, we asked subjects to repeat continuous sentences aloud or silently while we recorded electrical signals directly from the surface of the brain (electrocorticography (ECoG)). We then determined the relationship between cortical activity and speech output across different areas of cortex and at sub-second timescales. The results highlight a spatio-temporal progression of cortical involvement in the continuous speech process that initiates utterances in frontal-motor areas and ends with the monitoring of auditory feedback in superior temporal gyrus. Direct comparison of cortical activity related to overt versus covert conditions revealed a common network of brain regions involved in speech that may implement orthographic and phonological processing. Our results provide one of the first characterizations of the spatiotemporal electrophysiological representations of the continuous speech process, and also highlight the common neural substrate of overt and covert speech. These results thereby contribute to a refined understanding of speech functions in the human brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.