Evidence map›Paper›PMID 27875307›Full record

ArticleThe Journal of biological chemistry2016

Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway.

Zhijie Lin, Yong-Guo Zhang, Yinglin Xia, Xiulong Xu, Xinan Jiao, Jun Sun

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 57 citations in OpenAlex.

  1. Functional characterization of iucC and iucD in iron acquisition and virulence of Cronobacter sakazakii.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Molecular strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Review
  4. Article
  5. Infection biology ofEcoSal Plus · 2024
    Review
  6. Article
  7. Article
  8. Pyroptosis regulation byFrontiers in immunology · 2024
    Review
  9. Establishment of aJournal of pathogens · 2024
    Article
  10. N-acyl homoserine lactonase attenuates the virulence ofAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. International journal of molecular sciences · 2021
    Review
  17. AvrA Exerts Inhibition of NF-κB Pathway in Its NaïveInternational journal of molecular sciences · 2020
    Article
  18. Article
  19. Article
  20. Frontiers in cellular and infection microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zhijie LinFrom the Jiangsu Key Laboratory of Zoonosis, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis and.
Yong-Guo Zhangthe Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, and.
Yinglin Xiathe Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, and.
Xiulong XuFrom the Jiangsu Key Laboratory of Zoonosis, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis and.
Xinan JiaoFrom the Jiangsu Key Laboratory of Zoonosis, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis and.
Jun SunFrom the Jiangsu Key Laboratory of Zoonosis, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis and junsun7@uic.edu.ORCID http://orcid.org/0000-0001-7465-3133
University of Illinois Chicago · USRush University Medical Center · US

Funding

Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK105118 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUN, JUN · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK105118
6 · The paper itself

Abstract

Salmonella pathogenesis studies to date have focused on Salmonella typhimurium, and the pathogenesis of a second major serotype, Salmonella enteritidis, is poorly understood. Salmonella spp. possess effector proteins that display biochemical activities and modulate host functions. Here, we generated a deletion mutant of the effector AvrA, S.E-AvrA

Indexed as

AnimalsBacterial ProteinsColonFemaleHumansIntestinal MucosaMAP Kinase Kinase 4MiceMice, Inbred C57BLMutant ProteinsMutationSalmonella enteritidisSalmonella Infections, AnimalSignal TransductionTight JunctionsZonula Occludens-1 ProteinAvrA protein, Salmonella entericaBacterial ProteinsMAP Kinase Kinase 4Mutant ProteinsTjp1 protein, mouseZonula Occludens-1 Proteinc-Jun N-terminal kinase (JNK)infectioninflammationSalmonella entericatight junction

Identifiers

PMID27875307
PMCPMC5207190
OpenAlexW2553357491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.