ArticleNature chemistry2016
Direct observation of subpicosecond vibrational dynamics in photoexcited myoglobin.
Article in Nature chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The first microseconds of the life of excited heptamethine cyanine revealed by femtosecond stimulated Raman spectroscopy.Communications chemistry · 2025Article
- Direct observation of two-channel photodissociation of carbon monoxide from the hemoglobin subunits.Nature communications · 2025Article
- Ultrafast spectroscopy of liquids using extreme-ultraviolet to soft-X-ray pulses.Nature reviews. Chemistry · 2025Review
- Structural Characterization of Fluorescent Proteins Using Tunable Femtosecond Stimulated Raman Spectroscopy.International journal of molecular sciences · 2023Article
- Photogrammetry of Ultrafast Excited-State Intramolecular Proton Transfer Pathways in the Fungal Pigment Draconin Red.Molecules (Basel, Switzerland) · 2023Article
- Carotenoid responds to excess energy dissipation in the LH2 complex from Rhodoblastus acidophilus.Photosynthesis research · 2022Article
- Towards understanding non-equivalence of α and β subunits within human hemoglobin in conformational relaxation and molecular oxygen rebinding.Chemical science · 2021Article
- Improved spectral resolution of the femtosecond stimulated Raman spectroscopy achieved by the use of the 2nd-order diffraction method.Scientific reports · 2021Article
- Accessing Excited State Molecular Vibrations by Femtosecond Stimulated Raman Spectroscopy.The journal of physical chemistry letters · 2020Article
- Femtosecond X-ray emission study of the spin cross-over dynamics in haem proteins.Nature communications · 2020Article
- Ultrafast Dynamics and Vibrational Relaxation in Six-Coordinate Heme Proteins Revealed by Femtosecond Stimulated Raman Spectroscopy.Journal of the American Chemical Society · 2020Article
- Photoinduced charge flow inside an iron porphyrazine complex.Chemical communications (Cambridge, England) · 2019Article
- Do Osmolytes Impact the Structure and Dynamics of Myoglobin?Molecules (Basel, Switzerland) · 2018Article
- Excited State Structural Evolution of a GFP Single-Site Mutant Tracked by Tunable Femtosecond-Stimulated Raman Spectroscopy.Molecules (Basel, Switzerland) · 2018Article
- Ultrafast photochemistry of the bcPhysical chemistry chemical physics : PCCP · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Determining the initial pathway for ultrafast energy redistribution within biomolecules is a challenge, and haem proteins, for which energy can be deposited locally in the haem moiety using short light pulses, are suitable model systems to address this issue. However, data acquired using existing experimental techniques that fail to combine sufficient structural sensitivity with adequate time resolution have resulted in alternative hypotheses concerning the interplay between energy flow among highly excited vibrational levels and potential concomitant electronic processes. By developing a femtosecond-stimulated Raman set-up, endowed with the necessary tunability to take advantage of different resonance conditions, here we visualize the temporal evolution of energy redistribution over different vibrational modes in myoglobin. We establish that the vibrational energy initially stored in the highly excited Franck-Condon manifold is transferred with different timescales into low- and high-frequency modes, prior to slow dissipation through the protein. These findings demonstrate that a newly proposed mechanism involving the population dynamics of specific vibrational modes settles the controversy on the existence of transient electronic intermediates.
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