ArticleeLife2016
Postictal behavioural impairments are due to a severe prolonged hypoperfusion/hypoxia event that is COX-2 dependent.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04028596 (StudY of Effect of Nimodipine and Acetaminophen on Postictal Symptoms After ECT), which is not on this map. Cited by 85 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
StudY of Effect of Nimodipine and Acetaminophen on Postictal Symptoms After ECT
Who cites it
85 citing papers in PubMed, 147 citations in OpenAlex.
- Dynamics of early electroencephalographic patterns and epileptic seizures in acute intracerebral hemorrhage: A prospective controlled study.Epilepsia · 2026Trial
- Exploring postictal recovery with acetaminophen or nimodipine: A randomized-controlled crossover trial.Annals of clinical and translational neurology · 2024Trial
- Trial
- Peri-ictal magnetic resonance imaging findings in pediatric seizures: a scoping review on pearls and pitfalls from a heterogeneous population.Translational pediatrics · 2026Review
- Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain.Epilepsia · 2026Article
- Escape behaviors are transiently modulated after acutely induced epileptic seizures in larval zebrafish.Scientific reports · 2026Article
- Target trial emulation of early acetaminophen use and mortality in critically ill stroke patients.Scientific reports · 2026Article
- Article
- Article
- Postictal resting-state connectivity changes after electroconvulsive therapy-induced seizures.European archives of psychiatry and clinical neuroscience · 2026Article
- Neural barcoding representing cortical spatiotemporal dynamics based on continuous-time Markov chains.Cell reports methods · 2026Article
- Predictors of etiology and drug resistance in children with new-onset focal seizures.Epilepsia open · 2026Article
- Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model.The Journal of physiology · 2026Review
- Induced epileptic seizures in larval zebrafish reveal a synaptic modulation associated with the post-ictal state.Brain communications · 2026Article
- Corticothalamic dynamics during postictal recovery of self-orientation after electroconvulsive therapy.Brain communications · 2026Article
- Reimagining procedural distress as a candidate quality domain in pediatric emergency medicine.Frontiers in pediatrics · 2026Article
- Tissue Oxygenation Dynamics During Seizure to Spreading Depolarization in Rat Brain.bioRxiv : the preprint server for biology · 2025Article
- Persistent Na+ current couples spreading depolarization to seizures in Scn8a gain-of-function mice.Brain : a journal of neurology · 2025Article
- Redefining the practical roles of psychiatrists in epilepsy care: A framework for collaboration in Japan.PCN reports : psychiatry and clinical neurosciences · 2025Review
- The Exchange Breathing Method for Seizure Intervention: A Historical and Scientific Review of Epilepsy and Its Evolving Therapeutic Paradigms.Journal of personalized medicine · 2025Review
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors at 1 institution in 2 countries.
Funding
Abstract
Seizures are often followed by sensory, cognitive or motor impairments during the postictal phase that show striking similarity to transient hypoxic/ischemic attacks. Here we show that seizures result in a severe hypoxic attack confined to the postictal period. We measured brain oxygenation in localized areas from freely-moving rodents and discovered a severe hypoxic event (pO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.