Evidence map›Paper›PMID 27873900›Full record

ArticleSensors (Basel, Switzerland)2008

An Electrochemical DNA Biosensor Developed on a Nanocomposite Platform of Gold and Poly(propyleneimine) Dendrimer.

Omotayo Arotiba, Joseph Owino, Everlyne Songa, Nicolette Hendricks, Tesfaye Waryo, Nazeem Jahed, Priscilla Baker, Emmanuel Iwuoha

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Omotayo ArotibaSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. oarotiba@uwc.ac.za.
Joseph OwinoSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. jowino@uwc.ac.za.
Everlyne SongaSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. esonga@uwc.a.za.
Nicolette HendricksSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. nhendricks@uwc.ac.za.
Tesfaye WaryoSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. twaryo@uwc.ac.za.
Nazeem JahedSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. njahed@uwc.ac.za.
Priscilla BakerSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. pbaker@uwc.ac.za.
Emmanuel IwuohaSensorLab, Department of Chemistry, University of the Western Cape, Bellville, Cape Town 7535, South Africa. eiwuoha@uwc.ac.za.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An electrochemical DNA nanobiosensor was prepared by immobilization of a 20mer thiolated probe DNA on electro-deposited generation 4 (G4) poly(propyleneimine) dendrimer (PPI) doped with gold nanoparticles (AuNP) as platform, on a glassy carbon electrode (GCE). Field emission scanning electron microscopy results confirmed the codeposition of PPI (which was linked to the carbon electrode surface by C-N covalent bonds) and AuNP ca 60 nm. Voltammetric interrogations showed that the platform (GCE/PPI-AuNP) was conducting and exhibited reversible electrochemistry (E°' = 235 mV) in pH 7.2 phosphate buffer saline solution (PBS) due to the PPI component. The redox chemistry of PPI was pH dependent and involves a two electron, one proton process, as interpreted from a 28 mV/pH value obtained from pH studies. The charge transfer resistance (R

Indexed as

DNAelectrochemical DNA biosensorelectrochemical impedance spectroscopygold nanoparticlePoly(propyleneimine) dendrimer

Identifiers

PMID27873900
PMCPMC3787416

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.