ArticleSensors (Basel, Switzerland)2008
Diagnosis of Intoxication by the Organophosphate VX: Comparison Between an Electrochemical Sensor and Ellman´s Photometric Method.
Article in Sensors (Basel, Switzerland), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Simple Chemical and Cholinesterase Methods for the Detection of Nerve Agents Using Optical Evaluation.Biosensors · 2023Review
- Computational design of a sensitive, selective phase-changing sensor protein for the VX nerve agent.Science advances · 2022Article
- EGFR and COX-2 Dual Inhibitor: The Design, Synthesis, and Biological Evaluation of Novel Chalcones.Molecules (Basel, Switzerland) · 2022Article
- Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights.Drug design, development and therapy · 2021Article
- Cholinesterases and Engineered Mutants for the Detection of Organophosphorus Pesticide Residues.Sensors (Basel, Switzerland) · 2018Review
- Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) study.International journal of molecular sciences · 2013Article
- Assessment of acetylcholinesterase activity using indoxylacetate and comparison with the standard Ellman's method.International journal of molecular sciences · 2011Article
- Time-course changes of acetylcholinesterase activity in blood and some tissues in rats after intoxication by Russian VX.Neurotoxicity research · 2009Article
- Evaluation of cholinesterase activities during in vivo intoxication using an electrochemical sensor strip - correlation with intoxication symptoms.Sensors (Basel, Switzerland) · 2009Article
- Variation of cholinesterase-based biosensor sensitivity to inhibition by organophosphate due to ionizing radiation.Sensors (Basel, Switzerland) · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An electrochemical sensor is introduced as a tool applicable for diagnosis of intoxication by cholinesterase inhibitors caused by the well-known nerve agent VX. The traditional Ellman method was chosen for comparison with the sensor's analytical parameters. Both methods are based on estimation of blood cholinesterase inhibition as a marker of intoxication. While Ellman´s method provided a limit of detection of 5.2´10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.