ArticleBMJ case reports2016
Intracranial venous thrombosis in a man taking clomiphene citrate.
Article in BMJ case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Impact of fertility treatments on headache disorders: a systematic review with an overview of treatment modalities.The journal of headache and pain · 2026Pooled it
- Article
- Clomiphene- induced pulmonary embolism.Journal of community hospital internal medicine perspectives · 2021Article
- Anabolic steroid use and ischaemic stroke in a young fitness enthusiast.BMJ case reports · 2021Article
- Pulmonary Embolism as a Rare Complication of Clomiphene Therapy: A Case Report and Literature Review.Case reports in endocrinology · 2021Article
- Clomiphene misuse and risk of severe cardiovascular events.European journal of clinical pharmacology · 2020Article
- Diagnosis and Management of Anabolic Androgenic Steroid Use.The Journal of clinical endocrinology and metabolism · 2019Review
- Clomiphene-induced myocardial infarction in a young male: A case report of a rare cardiovascular complication.Science progressArticle
- Understanding and managing the suppression of spermatogenesis caused by testosterone replacement therapy (TRT) and anabolic-androgenic steroids (AAS).Therapeutic advances in urologyReview
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clomiphene citrate is widely used by the female population for the management of a wide array of medical conditions especially those related to ovulation, but its use in male population remains controversial. Efficacy of clomiphene is not well established in male hypogonadism and infertility. Its side effects and complications are also poorly studied or reported. We present a case of a man with infertility issues for which he started receiving clomiphene citrate 3 weeks before presenting with progressive symptoms of headache, vomiting, transient blurred vision and diplopia, which eventually turned out to be the symptoms of intracranial venous thrombosis. After excluding the common causes of intracranial venous thrombosis and hypercoagulable state, clomiphene citrate seems the most likely culprit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.