Evidence map›Paper›PMID 27873272›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2017

Analysis of Viral and Cellular MicroRNAs in EBV-Infected Cells.

Rebecca L Skalsky

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Dairy consumption and hepatocellular carcinoma risk.Annals of translational medicine · 2021
    Review
  4. Epstein-Barr virus-encoded miR-BART5-5p upregulates PD-L1 through PIAS3/pSTAT3 modulation, worsening clinical outcomes of PD-L1-positive gastric carcinomas.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2020
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rebecca L SkalskyVaccine and Gene Therapy Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR, USA. skalsky@ohsu.edu.
Children's Cancer Therapy Development Institute · US

Funding

The Role of Viral and Cellular miRNAs in B-cell LymphomagenesisR00CA175181 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SKALSKY, REBECCA L · 2016 to 2018
$717k
The role of viral and cellular miRNAs in B-cell lymphomagenesisK99CA175181 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SKALSKY, REBECCA L · 2014 to 2015
$199k
NCI NIH HHS K99 CA175181NCI NIH HHS R00 CA175181
6 · The paper itself

Abstract

MicroRNAs are small, noncoding RNAs that posttranscriptionally regulate gene expression. The discovery of this relatively new mode of gene regulation as well as studies showing the prognostic value of viral and cellular miRNAs as biomarkers, such as in cancer progression, has stimulated the development of many methods to characterize miRNAs. EBV encodes 25 viral precursor microRNAs within its genome that are expressed during lytic and latent infection. In addition to viral miRNAs, EBV infection induces the expression of specific cellular oncogenic miRNAs, such as miR-155, miR-146a, miR-21, and others, that can contribute to the persistence of latently infected cells. This chapter describes several current techniques used to identify and detect the expression of viral and cellular miRNAs in EBV-infected cells.

Indexed as

Gene Expression RegulationEpstein-Barr Virus InfectionsGenes, ReporterGenome, ViralHerpesvirus 4, HumanHigh-Throughput Nucleotide SequencingHost-Pathogen InteractionsHumansMicroRNAsMultigene FamilyReal-Time Polymerase Chain ReactionRNA, ViralMicroRNAsRNA, ViralBARTBHRF1Deep sequencingLuciferase assayMicroRNAPrimer extensionRIP-seqRISCRNA isolationStem-loop qRT-PCR

Identifiers

PMID27873272
PMCPMC5685176
OpenAlexW2555848723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.