Evidence map›Paper›PMID 27873151›Full record

ArticleNeuroinformatics2017

A Stereotactic Probabilistic Atlas for the Major Cerebral Arteries.

Tora Dunås, Anders Wåhlin, Khalid Ambarki, Laleh Zarrinkoob, Jan Malm, Anders Eklund

Abstract read
In one paragraph

Article in Neuroinformatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. 4D flow MRI for non-invasive measurement of blood flow in the brain: A systematic review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Pooled it
  2. Article
  3. Article
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  5. Cerebrovascular morphology: Insights into normal variations, aging effects and disease implications.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tora DunåsDepartment of Radiation Sciences, Umeå University, S-901 87, Umeå, Sweden. tora.dunas@umu.se.ORCID 0000-0002-5911-9511
Anders WåhlinDepartment of Radiation Sciences, Umeå University, S-901 87, Umeå, Sweden.
Khalid AmbarkiDepartment of Radiation Sciences, Umeå University, S-901 87, Umeå, Sweden.
Laleh ZarrinkoobDepartment of Pharmacology and Clinical Neuroscience, Umeå University, S-901 87, Umeå, Sweden.
Jan MalmDepartment of Pharmacology and Clinical Neuroscience, Umeå University, S-901 87, Umeå, Sweden.
Anders EklundDepartment of Radiation Sciences, Umeå University, S-901 87, Umeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improved whole brain angiographic and velocity-sensitive MRI is pushing the boundaries of noninvasively obtained cerebral vascular flow information. The complexity of the information contained in such datasets calls for automated algorithms and pipelines, thus reducing the need of manual analyses by trained radiologists. The objective of this work was to lay the foundation for such automated pipelining by constructing and evaluating a probabilistic atlas describing the shape and location of the major cerebral arteries. Specifically, we investigated how the implementation of a non-linear normalization into Montreal Neurological Institute (MNI) space improved the alignment of individual arterial branches. In a population-based cohort of 167 subjects, age 64-68 years, we performed 4D flow MRI with whole brain volumetric coverage, yielding both angiographic and anatomical data. For each subject, sixteen cerebral arteries were manually labeled to construct the atlas. Angiographic data were normalized to MNI space using both rigid-body and non-linear transformations obtained from anatomical images. The alignment of arterial branches was significantly improved by the non-linear normalization (p < 0.001). Validation of the atlas was based on its applicability in automatic arterial labeling. A leave-one-out validation scheme revealed a labeling accuracy of 96 %. Arterial labeling was also performed in a separate clinical sample (n = 10) with an accuracy of 92.5 %. In conclusion, using non-linear spatial normalization we constructed an artery-specific probabilistic atlas, useful for cerebral arterial labeling.

Indexed as

AgedAtlases as TopicCerebral ArteriesFemaleHumansImage EnhancementImaging, Three-DimensionalMagnetic Resonance AngiographyMaleMiddle AgedPattern Recognition, Automated4D flow MRIAutomatic labelingCerebral arteriesProbabilistic atlasSpatial normalization

Identifiers

PMID27873151
PMCPMC5306162

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.