Evidence map›Paper›PMID 27873145›Full record

ArticleOral and maxillofacial surgery2017

Use of refrigerant spray of a propane/butane/isobutane gas mixture in the management of keratocystic odontogenic tumors: a preliminary study.

Eduardo Luis de Souza Cruz, Ana Karla da Silva Tabosa, Aline Semblano Carreira Falcão, Talita Tartari, Lucas Machado de Menezes, Edmar Tavares da Costa, José Thiers Carneiro Júnior

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In one paragraph

Article in Oral and maxillofacial surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Cryogens in dentistry.Medical gas research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Eduardo Luis de Souza CruzResident of Oral and Maxillofacial Surgery at Ophir Loyola Hospital, Avenida Governador Magalhães Barata, 992, Belém, PA, 66063-240, Brazil.
Ana Karla da Silva TabosaOphir Loyola Hospital, Avenida Governador Magalhães Barata, 992, Belém, PA, 66063-240, Brazil.
Aline Semblano Carreira FalcãoEvandro Chagas Institute, Rodovia BR-316 Km 7 s/n, Levilândia, Ananindeua, PA, 67030-000, Brazil.
Talita TartariBauru School of Dentistry, University of São Paulo- FOB-USP, Vila Nova, Cidade Universitária, Bauru, SP, 17012901, Brazil.
Lucas Machado de MenezesOral and Maxillofacial Surgeon of Ophir Loyola Hospital, Avenida Governador Magalhães Barata, 992, Belém, PA, 66063-240, Brazil.
Edmar Tavares da CostaLaboratory of Experimental Neuropatology, Barros Barreto Hospital, Federal University of Pará-UFPA, Rua dos Mundurucus, 4487, Guamá, PA, 66073-000, Brazil.
José Thiers Carneiro JúniorOral and Maxillofacial Surgeon of Ophir Loyola Hospital, Avenida Governador Magalhães Barata, 992, Belém, PA, 66063-240, Brazil. drthiers@hotmail.com.
Hospital de Magalhães Lemos · PTInstituto Evandro Chagas · BRUniversidade Cidade de São Paulo · BRUniversidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeKeratocystic odontogenic tumor (KCOT) is an aggressive benign tumor and the management by complete enucleation followed by cryotherapy maintains the inorganic bone matrix, resulting in better repair and reduces the rates of recurrence. A refrigerant spray with a propane/butane/isobutane gas mixture has been pointed to as an alternative to liquid nitrogen, because the device is easy to handle and contain within the cavity, providing better control and lower risk of injury to the adjacent soft tissue. Thus, the aim of this study was to evaluate the outcome of enucleation followed by cryosurgery using a refrigerant spray of this gas mixture in ten patients diagnosed with KCOT.

methodThe biggest lesions received a prior treatment consisting of marsupialization to decrease the tumor size. During the surgeries, the lesions were removed by enucleation and the surgical site was sprayed with the gas mixture.

resultsWound dehiscence was observed in all cases, which healed by the second intention. The mean follow-up period was 64.3 months (range 24-120 months). Eight of the ten patients showed no evidence of clinical or radiographic recurrence. Pathologic fractures and infections were not observed.

conclusionsThe results obtained suggest that enucleation followed by cryosurgery is an effective therapy for managing KCOT.

Indexed as

AdolescentAdultAerosolsButanesChildCryosurgeryFemaleHumansMaleMandibular NeoplasmsMiddle AgedOdontogenic CystsOdontogenic TumorsPropaneRetrospective StudiesAerosolsbutaneButanesPropaneCryosurgeryJaw neoplasmsKeratocystsOdontogenic tumors

Identifiers

PMID27873145
OpenAlexW2552397552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.