Evidence map›Paper›PMID 27873085›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2017

Quantitative Analysis of Supporting Cell Subtype Labeling Among CreER Lines in the Neonatal Mouse Cochlea.

Melissa M McGovern, Joseph Brancheck, Auston C Grant, Kaley A Graves, Brandon C Cox

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Reprogramming withPNAS nexus · 2024
    Article
  3. Expression ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Fbxo2Hearing research · 2023
    Article
  6. Article
  7. The Notch Ligand Jagged1 Is Required for the Formation, Maintenance, and Survival of Hensen's Cells in the Mouse Cochlea.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Melissa M McGovernDepartment of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL, 62711, USA.
Joseph BrancheckDepartment of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL, 62711, USA.
Auston C GrantDepartment of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL, 62711, USA.
Kaley A GravesDepartment of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL, 62711, USA.
Brandon C CoxDepartment of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL, 62711, USA. bcox@siumed.edu.
Southern Illinois University School of Medicine · US

Funding

Leica TCS SP5 Spectral LSCM for the Research Imaging FacilityS10RR027716 · NCRR · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI LIBERATI, TERESA · 2010 to 2010
$500k
NCRR NIH HHS S10 RR027716
6 · The paper itself

Abstract

Four CreER lines that are commonly used in the auditory field to label cochlear supporting cells (SCs) are expressed in multiple SC subtypes, with some lines also showing reporter expression in hair cells (HCs). We hypothesized that altering the tamoxifen dose would modify CreER expression and target subsets of SCs. We also used two different reporter lines, ROSA26

Indexed as

AnimalsAnimals, NewbornCochleaFemaleGenetic TechniquesMaleMiceTamoxifenTamoxifenCAG-eGFPCre/loxPFgfr3-iCreERmouse geneticsPlp-CreERProx1-CreERROSA26-tdTomatoSox2-CreER

Identifiers

PMID27873085
PMCPMC5352607
OpenAlexW2550538297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.