Evidence map›Paper›PMID 27872977›Full record

ArticleWorld journal of surgery2017

Hypertension Cure Following Laparoscopic Adrenalectomy for Hyperaldosteronism is not Universal: Trends Over Two Decades.

Takeshi Namekawa, Takanobu Utsumi, Tomoaki Tanaka, Mayuko Kaga, Hidekazu Nagano, Takashi Kono, Koji Kawamura, Naoto Kamiya, Takashi Imamoto, Hiroyoshi Suzuki and 1 more

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In one paragraph

Article in World journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Takeshi NamekawaDepartment of Urology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Takanobu UtsumiDepartment of Urology, Toho University Sakura Medical Center, Shimoshizu 564-1, Sakura-Shi, Chiba, 285-8741, Japan. takanobu.utsumi@med.toho-u.ac.jp.
Tomoaki TanakaDepartment of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Mayuko KagaDepartment of Urology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hidekazu NaganoDepartment of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Takashi KonoDepartment of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Koji KawamuraDepartment of Urology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Naoto KamiyaDepartment of Urology, Toho University Sakura Medical Center, Shimoshizu 564-1, Sakura-Shi, Chiba, 285-8741, Japan.
Takashi ImamotoDepartment of Urology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hiroyoshi SuzukiDepartment of Urology, Toho University Sakura Medical Center, Shimoshizu 564-1, Sakura-Shi, Chiba, 285-8741, Japan.
Tomohiko IchikawaDepartment of Urology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPToho University · JPToho University Medical Center Sakura Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic adrenalectomy has been established as a standard surgical method for unilateral primary aldosteronism. Meanwhile, the background characteristics of the patients undergoing adrenalectomy have changed over the last 20 years. The aim of this study was to investigate the changes in hypertension cure rates after laparoscopic adrenalectomy during the last two decades.

methodsThis retrospective clinical study included 176 patients who underwent unilateral laparoscopic adrenalectomy for primary aldosteronism from 1995 to 2015. The patients were divided into two groups by decade. The patients' baseline characteristics and the hypertension cure rates were compared between the two groups. Additionally, the values were re-examined based on predictive model predicting postoperative hypertension cure.

resultsThe hypertension cure rate decreased significantly from 51.8 to 31.1%. The following variables were significantly different between the two groups: age, sex, body mass index, history of diabetes mellitus, preoperative systolic and diastolic blood pressures, potassium level, and plasma renin activity.

conclusionsThis study showed that the number of patients with unfavorable conditions for hypertension cure after adrenalectomy has recently increased. The treatment goal for primary aldosteronism is not only to cure the hypertension but also to prevent organ disorders due to inappropriate aldosterone levels. Therefore, we recommend laparoscopic adrenalectomy for unilateral primary aldosteronism, even if hypertension is not always cured postoperatively. However, clinicians need to fully explain the postoperative hypertension outcomes to primary aldosteronism patients.

Indexed as

AdrenalectomyLaparoscopyAge FactorsBody Mass IndexDiabetes MellitusFemaleHumansHyperaldosteronismHypertensionMaleMiddle AgedPotassiumReninRetrospective StudiesSex FactorsPotassiumRenin

Identifiers

PMID27872977
OpenAlexW2556393246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.