Evidence map›Paper›PMID 27872877›Full record

ArticleData in brief2016

Data on spermatogenesis in rat males gestationally exposed to bisphenol A and high fat diets.

Pheruza Tarapore, Max Hennessy, Dan Song, Jun Ying, Bin Ouyang, Vinothini Govindarajah, Yuet-Kin Leung, Shuk-Mei Ho

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Perfluoroalkyl Chemicals and Male Reproductive Health: Do PFOA and PFOS Increase Risk for Male Infertility?International journal of environmental research and public health · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Pheruza TaraporeDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Cincinnati Cancer Center, Cincinnati, Ohio, USA.
Max HennessyDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Dan SongDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Jun YingDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Bin OuyangDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Vinothini GovindarajahDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Yuet-Kin LeungDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Cincinnati Cancer Center, Cincinnati, Ohio, USA.
Shuk-Mei HoDepartment of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Cincinnati Cancer Center, Cincinnati, Ohio, USA; Cincinnati Veteran Affairs Hospital Medical Center, Cincinnati, Ohio, USA.
University of Cincinnati · USUniversity of Cincinnati Medical Center · US

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 1992 to 2022
$35.4M
Susceptible Window of High Fat Diet/Bisphenol A Programming of Breast Cancer RiskU01ES019480 · NIEHS · UNIVERSITY OF CINCINNATI · PI HO, SHUK-MEI · 2010 to 2014
$2.2M
Chronic exposure to Biphenol A and uterine cancer risk markersU01ES020988 · NIEHS · UNIVERSITY OF CINCINNATI · PI HO, SHUK-MEI · 2011 to 2014
$796k
G-protein coupled receptor-30(GPR30):a putative new therapeutic target for PCaI01BX000675 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI HO, SHUK-MEI · 2011 to 2019
–
BLRD VA I01 BX000675NIEHS NIH HHS P30 ES006096NIEHS NIH HHS U01 ES019480NIEHS NIH HHS U01 ES020988
6 · The paper itself

Abstract

This data article contains supporting information regarding the research article entitled "High butter-fat diet and bisphenol A additively impair male rat spermatogenesis" (P. Tarapore, M. Hennessy, D. Song, J. Ying, B. Ouyang, V. Govindarajah, et al.,) [1]. Sprague-Dawley females were fed AIN, high fat butter, 17α-ethinyl estradiol, or high fat butter plus four bisphenol A doses (2500 µg/kg bw-d, 250 µg/kg bw-d, 25 µg/kg bw-d, and 2.5 µg/kg bw-d) before and during pregnancy. All diets were switched to AIN after the pups were born. Male offspring received testosterone (T)- and estradiol-17β (E2)-filled implants from postnatal day 70-210 for 20 weeks (T+E2 rat model). The testes were weighed, and examined for impairments in spermatogenesis.

Indexed as

Bisphenol ABPA, bisphenol AE2, estradiol-17βEE2, 17α-ethinyl estradiolEndocrine disrupting chemicalsHFB, high fat butterHFO, high fat olive oilHigh fat butterHigh fat olive oilkg bw-d, kg body-weight per dayPND, postnatal dayPS, pachytene SpermatocytesRS, round spermatidsTestisT, testosterone

Identifiers

PMID27872877
PMCPMC5107686
OpenAlexW2548281644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.