Evidence map›Paper›PMID 27872837›Full record

ArticleWorld journal of nephrology2016

Antineutrophil cytoplasmic antibodies crescentic allograft glomerulonephritis after sofosbuvir therapy.

Shilpa Gadde, Belinda Lee, Laura Kidd, Rubin Zhang

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A Spotlight on Drug-Induced Vasculitis.Current rheumatology reports · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shilpa GaddeShilpa Gadde, Belinda Lee, Laura Kidd, Rubin Zhang, Department of Nephrology and Hypertension, Tulane University School of Medicine, New Orleans, LA 70112, United States.
Belinda LeeShilpa Gadde, Belinda Lee, Laura Kidd, Rubin Zhang, Department of Nephrology and Hypertension, Tulane University School of Medicine, New Orleans, LA 70112, United States.
Laura KiddShilpa Gadde, Belinda Lee, Laura Kidd, Rubin Zhang, Department of Nephrology and Hypertension, Tulane University School of Medicine, New Orleans, LA 70112, United States.
Rubin ZhangShilpa Gadde, Belinda Lee, Laura Kidd, Rubin Zhang, Department of Nephrology and Hypertension, Tulane University School of Medicine, New Orleans, LA 70112, United States.
Tulane University · USCreative Research Enterprises (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antineutrophil cytoplasmic antibodies (ANCA) are well known to be associated with several types of vasculitis, including pauci-immune crescentic glomerulonephritis, a form of rapid progressive glomerular nephritis (RPGN). ANCA vasculitis has also been reported after administration of propylthiouracil, hydralazine, cocaine (adulterated with levimasole), allopurinol, penicillamine and few other drugs. All previously reported cases of drug-associated ANCA glomerulonephritis were in native kidneys. Sofosbuvir is a new and effective drug for hepatitis C virus infection. Here, we report a case of ANCA vasculitis and RPGN following sofosbuvir administration in a kidney transplant recipient. It also represents the first case of drug-associated ANCA vasculitis in a transplanted kidney. Further drug monitoring is necessary to elucidate the degree of association and possible causal effect of sofosbuvir and perinuclear ANCA vasculitis.

Indexed as

Antineutrophil cytoplasmic antibodyCrescentic glomerulonephritisKidney transplantSofosbuvirVasculitis

Identifiers

PMID27872837
PMCPMC5099601
OpenAlexW2547847695

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.