ArticleNeuroImage. Clinical2016
Identification of the stria medullaris thalami using diffusion tensor imaging.
Article in NeuroImage. Clinical, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Microsurgical Anatomy of the Posterior Commissure and Habenular Commissure in the Human Cadaveric Brain.Brain sciences · 2026Article
- The Targets of Deep Brain Stimulation in the Treatment of Treatment-Resistant Depression: A Review.Brain and behavior · 2025Review
- Topographical anatomy of the septum verum and its white matter connections.Scientific reports · 2024Article
- White Matter Tracts Associated With Deep Brain Stimulation Targets in Major Depressive Disorder: A Systematic Review.Frontiers in psychiatry · 2022Review
- Laterality and Sex Differences of Human Lateral Habenula Afferent and Efferent Fiber Tracts.Frontiers in neuroscience · 2022Article
- Awakening Neuropsychiatric Research Into the Stria Medullaris: Development of a Diffusion-Weighted Imaging Tractography Protocol of This Key Limbic Structure.Frontiers in neuroanatomy · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeep brain stimulation (DBS) via anatomical targeting of white matter tracts defined by diffusion tensor imaging (DTI) may be a useful tool in the treatment of pathologic neurophysiologic circuits implicated in certain disease states like treatment resistant depression (TRD). We sought to determine if DTI could be used to define the stria medullaris thalami (SM), the major afferent white matter pathway to the lateral habenula (LHb), a thalamic nucleus implicated in the pathophysiology of TRD.
methodsProbabilistic DTI was performed on ten cerebral hemispheres in five patients who underwent preoperative MRI for DBS surgery. Manual identification of the LHb on axial T1 weighted MRI was used for the initial seed region for tractography. Variations in tractography depending on chosen axial slice of the LHb and chosen voxel within the LHb were also assessed.
resultsIn all hemispheres the SM was reliably visualized. Variations in chosen axial seed slice as well as variations in single seed placement did not lead to significant changes in SM tractography.
conclusionsProbabilistic DTI can be used to visualize the SM which may ultimately provide utility for direct anatomic targeting in DBS surgery.
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