Evidence map›Paper›PMID 27872694›Full record

ArticleBasic and clinical neuroscience2016

Long-Term Treatment by Vitamin B

Jalal Zaringhalam, Akhtar Akbari, Alireza Zali, Homa Manaheji, Vida Nazemian, Mahdi Shadnoush, Somayeh Ezzatpanah

Open access · diamondAbstract read
In one paragraph

Article in Basic and clinical neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Serum vitamins andFrontiers in immunology · 2026
    Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Vitamin B1 Helps to LimitFrontiers in immunology · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jalal ZaringhalamNeurophysiology Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Akhtar AkbariFunctional Neurosurgery Research Center of Shohada' Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Alireza ZaliFunctional Neurosurgery Research Center of Shohada' Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Homa ManahejiDepartment of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Vida NazemianDepartment of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahdi ShadnoushDepartment of Clinical Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Somayeh EzzatpanahNeuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImmune system is involved in the etiology and pathophysiology of inflammation and vitamins are important sources of substances inducing nonspecific immunomodulatory effects. Given the proinflammatory role of cytokines in the inflammation and pain induction, this study aimed to assess the effects of long-term administration of vitamin B

methodsOn the first day of study, inflammation was induced by intraplantar injection of complete Freund's adjuvant (CFA) in the hindpaws of rats. Vitamin B

resultsThe results indicated that vitamin B

conclusionAnti-inflammatory and antihyperalgesic effects of vitamin B1 during CFA-induced arthritis, more specifically after chronic vitamin B

Indexed as

Complete Freund's Adjuvant (CFA)HyperalgesiaInflammationTNF-αVitamin B1

Identifiers

PMID27872694
PMCPMC5102562
OpenAlexW2525851915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.