Evidence map›Paper›PMID 27872606›Full record

ArticleFrontiers in neurology2016

An Exploratory Study to Detect Ménière's Disease in Conventional MRI Scans Using Radiomics.

E L van den Burg, M van Hoof, A A Postma, A M L Janssen, R J Stokroos, H Kingma, R van de Berg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

E L van den BurgDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center , Maastricht , Netherlands.
M van HoofDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center , Maastricht , Netherlands.
A A PostmaDepartment of Radiology, Maastricht University Medical Center , Maastricht , Netherlands.
A M L JanssenDepartment of Methodology and Statistics, School for Public Health and Primary Care (CAPHRI), Maastricht University , Maastricht , Netherlands.
R J StokroosDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center , Maastricht , Netherlands.
H KingmaDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, Maastricht, Netherlands; Faculty of Physics, Tomsk State University, Tomsk, Russian Federation.
R van de BergDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, Maastricht, Netherlands; Faculty of Physics, Tomsk State University, Tomsk, Russian Federation.
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this exploratory study was to investigate whether a quantitative image analysis of the labyrinth in conventional magnetic resonance imaging (MRI) scans using a radiomics approach showed differences between patients with Ménière's disease (MD) and the control group. MATERIALS AND

methodsIn this retrospective study, MRI scans of the affected labyrinths of 24 patients with MD were compared to the MRI scans of labyrinths of 29 patients with an idiopathic asymmetrical sensorineural hearing loss. The 1.5- and 3-T MRI scans had been previously made in a clinical setting between 2008 and 2015. 3D Slicer 4.4 was used to extract several substructures of the labyrinth. A quantitative analysis of the normalized radiomic image features was performed in Mathematica 10. The image features of the two groups were statistically compared.

resultsFor numerous image features, there was a statistically significant difference (

conclusionIn this exploratory study, several differences were found in image features between the MD group and the control group by using a quantitative radiomics approach on high resolution T2-weighted MRI scans of the labyrinth. Further research should be aimed at validating these results and translating them in a potential clinical diagnostic method to detect MD in MRI scans.

Indexed as

3D modelsimaginglabyrinthMénière’s diseaseMRIquantitative image analysisradiomicsvertigo

Identifiers

PMID27872606
PMCPMC5098221
OpenAlexW2555689301

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.