ArticlePain research & management2016
Effect of Intravenous High Dose Vitamin C on Postoperative Pain and Morphine Use after Laparoscopic Colectomy: A Randomized Controlled Trial.
Article in Pain research & management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Placebo Controlled Trial of Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
Does Vitamin C Level Effect Postoperative Analgesia in Orthognathic Surgery: a Preliminary Study?
Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Pooled it
- The Effect of Perioperative Vitamin C on Postoperative Analgesic Consumption: A Meta-Analysis of Randomized Controlled Trials.Nutrients · 2020Pooled it
- Pooled it
- Pharmacologic interventions for fatigue in cancer and transplantation: a meta-analysis.Current oncology (Toronto, Ont.) · 2018Pooled it
- Effect of Vitamin C on bleeding and pain after kidney biopsy: a randomized controlled trial.BMC medicine · 2026Trial
- Comparison of the effects of preoperative melatonin or vitamin C administration on postoperative analgesia.Bosnian journal of basic medical sciences · 2020Trial
- Review
- Efficacy of transversus abdominis plane block in preventing chronic postsurgical pain: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Vitamin C as an Adjuvant Analgesic Therapy in Postoperative Pain Management.Journal of clinical medicine · 2025Review
- High-dose vitamin C as a metabolic treatment of cancer: a new dimension in the era of adjuvant and intensive therapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- The Use of High-Dose Intravenous L-Ascorbate in Pain Therapy: Current Evidence from the Literature.Pain and therapy · 2024Review
- Anti-Inflammatory Effect of Vitamin C during the Postoperative Period in Patients Subjected to Total Knee Arthroplasty: A Randomized Controlled Trial.Journal of personalized medicine · 2023Article
- Nutrient Therapy for the Improvement of Fatigue Symptoms.Nutrients · 2023Review
- Effect of ImmatureMedicina (Kaunas, Lithuania) · 2023Article
- Article
- The Influence of Dietary Supplementations on Neuropathic Pain.Life (Basel, Switzerland) · 2022Review
- Review
- Clinical efficacy and safety of oral and intravenous vitamin C use in patients with malignant diseases.Journal of cancer research and clinical oncology · 2021Review
- Glutathione and Glutathione-Like Sequences of Opioid and Aminergic Receptors Bind Ascorbic Acid, Adrenergic and Opioid Drugs Mediating Antioxidant Function: Relevance for Anesthesia and Abuse.International journal of molecular sciences · 2020Article
- Vitamin C, Pain and Opioid Use Disorder.Integrative medicine (Encinitas, Calif.) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.