Evidence map›Paper›PMID 27872250›Full record

ArticleThe Journal of cell biology2016

Axon degeneration: Linking axonal bioenergetics to myelin.

Bogdan Beirowski, Elisabetta Babetto, Lawrence Wrabetz

Abstract read
In one paragraph

Article in The Journal of cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bogdan BeirowskiHunter James Kelly Research Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203.
Elisabetta BabettoHunter James Kelly Research Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203.
Lawrence WrabetzHunter James Kelly Research Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203 bogdanbe@buffalo.edu lwrabetz@buffalo.edu.

Funding

Pathogenesis of Myelin Protein Zero Neuropathies in Transgenic MiceR01NS055256 · NINDS · ISTITUTO SCIENTIFICO SAN RAFFAELE · PI WRABETZ, LAWRENCE · 2006 to 2010
$1.2M
Pathogenesis of Myelin Protein Zero Neuropathies in Transgenic MiceR56NS096104 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WRABETZ, LAWRENCE · 2016 to 2016
$396k
NINDS NIH HHS R01 NS055256NINDS NIH HHS R56 NS096104
6 · The paper itself

Abstract

The mechanisms by which axonal degeneration occurs, even in the presence of apparently normal myelin sheaths, remain unknown. In this issue, Yin et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201607099) study mutant mice in which proteolipid protein is replaced by the peripheral myelin protein P

Indexed as

Energy MetabolismAnimalsAxonal TransportAxonsMice, Mutant StrainsMitochondriaMitochondrial DynamicsModels, BiologicalMyelin SheathNerve DegenerationOligodendroglia

Identifiers

PMID27872250
PMCPMC5119944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.