ArticlePlant physiology2017
The Transcription Factor ATHB5 Affects GA-Mediated Plasticity in Hypocotyl Cell Growth during Seed Germination.
Article in Plant physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- A cellular view of seed development and germination.The Plant cell · 2026Review
- Holistic overview of regulatory networks governing seed dormancy and germination in plants.Science China. Life sciences · 2026Review
- Article
- Establishment of single-cell transcriptional states during seed germination.Nature plants · 2024Article
- The dimorphic diaspore model Aethionema arabicum (Brassicaceae): Distinct molecular and morphological control of responses to parental and germination temperatures.The Plant cell · 2024Article
- Red LED Light Improves Pepper (International journal of molecular sciences · 2023Article
- Article
- A Molecular Signal Integration Network Underpinning Arabidopsis Seed Germination.Current biology : CB · 2020Article
- FRUITFULL Is a Repressor of Apical Hook Opening inInternational journal of molecular sciences · 2020Article
- An Updated Overview on the Regulation of Seed Germination.Plants (Basel, Switzerland) · 2020Review
- Complex Molecular Evolution and Expression of Expansin Gene Families in Three Basic Diploid Species ofInternational journal of molecular sciences · 2020Article
- Microtubule self-organisation during seed germination in Arabidopsis.BMC biology · 2020Article
- Overexpression of MaizeFrontiers in plant science · 2020Article
- Aquaporins influence seed dormancy and germination in response to stress.Plant, cell & environment · 2019Article
- A Regulatory Module Controlling GA-Mediated Endosperm Cell Expansion Is Critical for Seed Germination in Arabidopsis.Molecular plant · 2019Article
- Multiple Links between HD-Zip Proteins and Hormone Networks.International journal of molecular sciences · 2018Review
- Extensive transcriptomic and epigenomic remodelling occurs during Arabidopsis thaliana germination.Genome biology · 2017Article
- Temperature variability is integrated by a spatially embedded decision-making center to break dormancy inProceedings of the National Academy of Sciences of the United States of America · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Gibberellic acid (GA)-mediated cell expansion initiates the seed-to-seedling transition in plants and is repressed by DELLA proteins. Using digital single-cell analysis, we identified a cellular subdomain within the midhypocotyl, whose expansion drives the final step of this developmental transition under optimal conditions. Using network inference, the transcription factor ATHB5 was identified as a genetic factor whose localized expression promotes GA-mediated expansion specifically within these cells. Both this protein and its putative growth-promoting target EXPANSIN3 are repressed by DELLA, and coregulated at single-cell resolution during seed germination. The cellular domains of hormone sensitivity were explored within the Arabidopsis (Arabidopsis thaliana) embryo by putting seeds under GA-limiting conditions and quantifying cellular growth responses. The middle and upper hypocotyl have a greater requirement for GA to promote cell expansion than the lower embryo axis. Under these conditions, germination was still completed following enhanced growth within the radicle and lower axis. Under GA-limiting conditions, the athb5 mutant did not show a phenotype at the level of seed germination, but it did at a cellular level with reduced cell expansion in the hypocotyl relative to the wild type. These data reveal that the spatiotemporal cell expansion events driving this transition are not determinate, and the conditional use of GA-ATHB5-mediated hypocotyl growth under optimal conditions may be used to optionally support rapid seedling growth. This study demonstrates that multiple genetic and spatiotemporal cell expansion mechanisms underlie the seed to seedling transition in Arabidopsis.
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