Evidence map›Paper›PMID 27872240›Full record

ArticleInfection and immunity2017

The Staphylococcus aureus AirSR Two-Component System Mediates Reactive Oxygen Species Resistance via Transcriptional Regulation of Staphyloxanthin Production.

Jeffrey W Hall, Junshu Yang, Haiyong Guo, Yinduo Ji

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 72 citations in OpenAlex.

  1. ThebioRxiv : the preprint server for biology · 2026
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  2. Host-driven remodelling of theMicrobiology (Reading, England) · 2026
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  5. CcpA promotesmLife · 2025
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  11. Article
  12. Review
  13. Crosstalk involving two-component systems inJournal of bacteriology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. International journal of molecular sciences · 2023
    Article
  18. Article
  19. Synergistic Antibacterial Effect of Ethyl Acetate Fraction ofAdvances in pharmacological and pharmaceutical sciences · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Jeffrey W HallDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.
Junshu YangDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.
Haiyong GuoDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.
Yinduo JiDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA jixxx002@umn.edu.
University of Minnesota · US

Funding

A Novel Essential Regulator of Staphylococcus aureusR01AI057451 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JI, YINDUO · 2005 to 2008
$969k
NIAID NIH HHS R01 AI057451
6 · The paper itself

Abstract

Staphylococcus aureus is an important opportunistic pathogen and is the etiological agent of many hospital- and community-acquired infections. The golden pigment, staphyloxanthin, of S. aureus colonies distinguishes it from other staphylococci and related Gram-positive cocci. Staphyloxanthin is the product of a series of biosynthetic steps that produce a unique membrane-embedded C

Indexed as

Gene Expression Regulation, BacterialTranscription, GeneticBacterial ProteinsHumansHydrogen PeroxideMicrobial ViabilityMutationPigments, BiologicalPromoter Regions, GeneticProtein BindingReactive Oxygen SpeciesSigma FactorStaphylococcal InfectionsStaphylococcus aureusXanthophyllsBacterial ProteinsHydrogen PeroxidePigments, BiologicalReactive Oxygen SpeciesSigma FactorstaphyloxanthinXanthophyllsAirSRS. aureusstaphyloxanthintranscriptional regulationtwo-component regulatory systems

Identifiers

PMID27872240
PMCPMC5278164
OpenAlexW2554276247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.