Evidence map›Paper›PMID 27872185›Full record

ArticleThe Journal of biological chemistry2016

The Major Replicative Histone Chaperone CAF-1 Suppresses the Activity of the DNA Mismatch Repair System in the Cytotoxic Response to a DNA-methylating Agent.

Lyudmila Y Kadyrova, Basanta K Dahal, Farid A Kadyrov

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lyudmila Y KadyrovaFrom the Department of Biochemistry and Molecular Biology, Southern Illinois University, School of Medicine, Carbondale, Illinois 62901.
Basanta K DahalFrom the Department of Biochemistry and Molecular Biology, Southern Illinois University, School of Medicine, Carbondale, Illinois 62901.
Farid A KadyrovFrom the Department of Biochemistry and Molecular Biology, Southern Illinois University, School of Medicine, Carbondale, Illinois 62901 fkadyrov@siumed.edu.
Southern Illinois University School of Medicine · US

Funding

DNA mismatch repair in the nucleosomal environmentR01GM095758 · NIGMS · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI KADYROV, FARID · 2013 to 2017
$1.2M
NIGMS NIH HHS R01 GM095758
6 · The paper itself

Abstract

The DNA mismatch repair (MMR) system corrects DNA mismatches in the genome. It is also required for the cytotoxic response of O

Indexed as

Antibiotics, AntineoplasticBleomycinDNA MethylationDNA Mismatch RepairGene Expression Regulation, FungalHEK293 CellsHumansMethylnitronitrosoguanidineRibonucleasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAntibiotics, AntineoplasticBleomycinMethylnitronitrosoguanidinePOP2 protein, S cerevisiaeRibonucleasesSaccharomyces cerevisiae ProteinscancerDNA mismatch repairDNA replicationgenomic instabilityhistone chaperonemutL homolog 1 (MLH1)

Identifiers

PMID27872185
PMCPMC5207156
OpenAlexW2556595635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.